Pharmaceutical Analysis

Separation Science, in collaboration with Shimadzu, offers a series of application notes covering everything from a high efficiency workflow for simple fractionation, examples of preparative purification and comprehensive fractionation of herbal...

This eBook contains a selection of application notes relevant for pharmaceutical and biopharmaceutical analysis using HPLC / (U)HPLC or LC-MS/MS.

Separation Science, in collaboration with Shimadzu, offers a series of application notes describing the quantitation of various nitrosamines in drugs and solvents using its LC/MS or GC/MS instruments. Click below to download your personal copies.

Separation Science, in collaboration with Shimadzu, offers a series of application notes exploring the latest and most up-to-date solutions for COVID-19 drug analysis. Click below to download your personal copies.

This article describes the stacked injection functionality of Shimadzu's Nexera UC Prep system to improve the efficiency of preparative operations.

This application note describes a method for the analysis of Class 2 solvents (water-soluble samples) that are unsuited to Headspace GC methods.

This application note describes the high-speed analysis of linezolid following the draft guidance of International Harmonization of Pharmacopoeias.

This application note will help you readily perform comprehensive targeted analysis of cell culture media and understand how to identify and quantify unknown cell culture media components with high accuracy using Q-TOF MS/MS.

This application note will help you understand how trap-free 2D LC-MS allows online conversion of non-volatile to volatile mobile phase conditions and how the LCMS-9030’s high mass accuracy can be used to conduct structural analysis of impurities.

This application note describes a method for the preparative purification of Ibuprofen and its analogs using the Prominence™ UFPLC designed to improve the efficiency of your workflow.

This application note demonstrates a method for the high-speed analysis of pramipexole following the draft guidance of International Harmonization of Pharmacopoeias. It uses Shimadzu's integrated LC system, the Nexera™ - i MT. 

This application demonstrates an effective method for the analysis irbesartan using Shimadzu's integrated LC system, the Nexera™ - i MT. 

This study describes the LCMS bioanalysis of antibody drugs using the Fab-selective proteolysis "nSMOL Method" offering an improvement of reaction conditions for automated analyses.

To better prepare QA/QC lab analysts and technicians for digitalisation, Singapore Polytechnic’s (SP) School of Chemical and Life Sciences (CLS) and Shimadzu, have set up a Scalable, Manageable, Automated, Regulated and Total-Compliant Laboratory...

Learn how to assure data integrity in the laboratory from the perspective of laboratory management, supervisors and technicians.

There is currently a great deal of regulatory focus on data integrity, especially in the QC Laboratory. This is causing...