Pharmaceutical Analysis

In this article, from Issue 12 of the Analytix Reporter, produced by Merck, difluoroacetic acid (DFA) is discussed as a suitable alternative to TFA and FA for LC-UV/MS analysis.

In this article, from Issue 12 of the Analytix Reporter, produced by Merck, an LC-UV/MS method is presented using a corresponding E&L certified reference material (CRM) mix for the LC determination of extractables and leachables.

In this article, from Issue 12 of the Analytix Reporter, produced by Merck, three step-by-step protocols to monitor critical quality attributes (CQAs) of monoclonal antibodies were developed using adalimumab as an example.

Conventional protein digestion procedures used in peptide mapping are lengthy and introduce significant amounts of oxidation and deamidation artifacts. In this article, from Issue 11 of the Analytix Reporter, produced by Merck, the optimized...

The therapeutic potential of biologic modalities has increased, driving an inevitable move toward exploring more complex biotherapeutic molecule classes. As biotherapeutics become more complex, there is still a demand for superior quantification...

Tosoh Bioscience has produced Volume 1 of its 'Biopharmaceutical Application Notebook' for the (U)HPLC analysis of biomolecules. This essential application notebook will keep you informed of all the latest developments in the biopharmaceutical...

Tosoh Bioscience has produced Volume 1 of its 'Biopharmaceutical Application Notebook' for the (U)HPLC analysis of biomolecules. This essential application notebook will keep you informed of all the latest developments in the biopharmaceutical...

SCIEX has produced an application note describing the N-glycosylation profiling of carbohydrates associated with therapeutic antibodies for faster, more cost-effective development of biologics.

Shimadzu has produced an application note describing phospholipid analysis for four types of mouse tissues performed by precursor ion scan (PIS) or neutral loss scan (NLS) with a triple quadrupole mass spectrometer.

Looking to improve the yield and purity of your target proteins? Then don't miss this on-demand presentation...

Camag has produced an application note describing an HPTLC-MS method for confirming the presence of cannabinoids in Cannabis sativa. 

Tosoh Bioscience LLC, a provider of chromatographic resins for the purification of biopharmaceutical drugs in commercial manufacturing processes, has announced the introduction of TOYOPEARL AF-rProtein L-650F, a Protein L resin that exhibits the...

Get expert answers to your standard biologics characterization challenges with the new X500B QTOF system from SCIEX. The X500B system is one of the smallest, most reliable high-resolution QTOF instruments available. New, user-friendly SCIEX OS...

UCT has produced an application note outlining a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) technique that has been optimized to extract common prescription and illicit drugs from liver prior to analysis by LC-MS/MS.

With the number of new biologics being approved each year quadrupling since 2004-2008, biotherapeutics have become an important segment in the pharmaceutical industry. SCIEX has prepared for this market dynamic by developing innovative technologies...