Pharma Science

Principles of HPLC Validation - Training Module 1: Introduction

A short course in the systematic validation of HPLC methods. We start by taking an overview of the validation process and review some of the key references that will be useful in setting up a validation process. We also discuss the terminology...

Reaction Monitoring with UltraPerformance Convergence Chromatography

Once a chemical hit is found through a library screening process and verified, the synthetic route is then optimized. This step involves an iterative process of synthesis and reactivity measurements of the new compound(s) to further develop the...

Why CE (Capillary Electrophoresis)?

The capillary electrophoresis (CE)techniques have been around since the 1980s, and commercial instruments available since the end of that decade. So why would we start on such a topic now? There are several indications for a growing interest in...

Practical Considerations for Achiral Analysis of Pharmaceutical Compounds Using Convergence Chromatography

In convergence chromatography (CC), the modes of interaction between the stationary phase and the solute are numerous, including hydrogen bonding, hydrophobic interactions, dipolar and polarizability interactions and solute partitioning [1]....

The keys to understanding isocratic HPLC

SUCCESSFUL CHROMATOGRAPHY STARTS AT THE BEGINNING

Understanding the basics of any chromatographic technique is the first step towards achieving your analytical goals and allowing correct decision making and effective pharmaceutical method...

    

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