Pharma Science

[On-Demand Webinar] Accelerating Large Molecule LC-MS Method Development

Rapid development of sensitive and selective peptide bioanalytical methods are required to support the expanding protein component of pharmaceutical companies’ drug pipeline. Choosing the best MRM for a large molecule peptide or protein is a...

Biopharmaceutical Application Notebook for (U)HPLC Analysis of Biomolecules

Tosoh Bioscience has produced Volume 1 of its 'Biopharmaceutical Application Notebook' for the (U)HPLC analysis of biomolecules. This essential application notebook will keep you informed of all the latest developments in the biopharmaceutical...

HPAE-PAD - A very useful tool for glycan analysis

Looking for analytical advantage with your glycan and glycosylation analysis? If so, then high-performance anion-exchange chromatography with pulsed amperometric detection may well be worth a look...

DAR Analysis of Antibody-Drug Conjugates

Tosoh Bioscience has produced an application note describing drug-to-antibody ratio (DAR) analysis of an antibody-drug conjugate by hydrophobic interaction chromatography (HIC).

Practical HPLC for Biopharmaceuticals – Training Module 1: Isocratic HPLC Basics

Although “small molecule” and “biopolymer” separations have traditionally been considered as separate activities, analysts in the biopharmaceutical industry regularly have to deal with both. Fortunately, the underlying principles of...

Trends in IC for pharmaceutical analysis - expert interview, part 2

This is the second part of our discussion with Dr Jeffrey Rohrer, Director of Applications for ion chromatography (IC) products at Thermo Fisher Scientific for his thoughts on the evolving role of IC in regulated pharmaceutical analysis...

New Mass Spectrometer Platform Offers Greater Quantitative Sensitivity, Speed and Reproducibility

New Q Exactive HF-X Orbitrap mass spectrometer enables scientists to advance disease research and drug discovery.

Trends in IC for pharmaceutical analysis - expert interview, part 1...

We talked with Dr Jeffrey Rohrer, Director of Applications for ion chromatography (IC) products at Thermo Fisher Scientific for his thoughts on the evolving role of IC in regulated pharmaceutical analysis...

Extractables and Leachables from Single Use Bioprocess Systems

Extractables and leachables (E&Ls) are small molecules present in a polymer system including antioxidants, surfactants, slip agents, plasticizers, acid scavengers, cross linking agents, residual monomers and oligomers, polymerization side...

Discover Single-Digit ppm Host Cell Proteins in Purified Antibody Samples

Recombinant biopharmaceutical proteins are expressed in host cell systems that contain numerous host cell proteins (HCPs). Even after a series of purifications, low levels of HCPs can remain in the purified biotherapeutics, which could reduce...

Peptide Mapping- A Comprehensive Workflow Solution from Sample to Answer

Peptide mapping is vital to understanding the structure of proteins and monitoring critical quality attributes. To create effective, high-quality biotherapeutics, you have to get this right. Renowned for accuracy and reliability, Agilent offers a...

2D-LC Solutions for the Analysis of Biopharmaceuticals

The presentation summarizes the latest updates for the analysis of biopharmaceuticals using the Agilent 1290 Infinity II 2D-LC Solution. After a short introduction to the principle mode of operation, I will explain the latest 2D-LC modes;...

     

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