Pharmaceutical Analysis Blog

The importance of particle pore diameter for biomacromolecule separations

Recently, the evolution of middle to large biomacromolecules such as peptides or proteins is apparent in the market of pharmaceutical drugs in addition to traditional active ingredients based on small molecules. The use of peptides for clinical...

Methods and Applications to Improve Pharmaceutical Workflows

Benefit from a series of educational resources aimed at pharmaceutical scientists, ranging from pharmaceutical impurity method development, to a complete HPLC workflow comprising multiple detectors, to strategies to improve productivity and...

Download now the Bioanalysis Quantitation Applications eBook Vol 2

The therapeutic potential of biologic modalities has increased, driving an inevitable move toward exploring more complex biotherapeutic molecule classes. As biotherapeutics become more complex, there is still a demand for superior quantification...

Analysis of a bispecific monoclonal antibody with SEC-MS

Looking for an effective method for monoclonal antibody analysis? SEC-MS could be the answer...

Why CE (Capillary Electrophoresis)?

The capillary electrophoresis (CE)techniques have been around since the 1980s, and commercial instruments available since the end of that decade. So why would we start on such a topic now? There are several indications for a growing interest in...

Easy characterisation workflows in therapeutic protein analysis

Looking for new and improved technologies to advance your peptide mapping strategies? Do you want to overcome automation problems with your therapeutic protein workflows? If so, signup for this educational presentation...

The keys to understanding isocratic HPLC

SUCCESSFUL CHROMATOGRAPHY STARTS AT THE BEGINNING

Understanding the basics of any chromatographic technique is the first step towards achieving your analytical goals and allowing correct decision making and effective pharmaceutical method...

The role of light scattering in biopharmaceutical formulation development

Are you involved in biopharmaceutical research? Would you like to find out more about the role of light scattering and associated techniques in characterizing biological molecules? This presentation from Separation Science, in collaboration with...

A biopharma collaboration - NIBRT and Thermo Fisher Scientific

Biopharmaceuticals represent protein molecules produced by genetically engineered living cells using large scale industrial bioprocessing. The complexity of these molecules requires advanced analytical characterisation strategies to ensure that...

Perform LCMS bioanalysis of antibody drugs using new nSMOL technology

This study describes the LCMS bioanalysis of antibody drugs using the Fab-selective proteolysis "nSMOL Method" offering an improvement of reaction conditions for automated analyses.

Get more information in less time: Improve your peptide mapping and PTM analysis skills

Peptide mapping is critical for characterizing protein drugs and monitoring product critical quality attributes (CQAs) in biopharma. Due to the heterogenous nature of protein drugs, comprehensive analytical characterization is required for...

Comparing in-solution digestion approaches to quantify therapeutic mAb modifications

Do you work with therapeutic recombinant mAbs? Need to understand the extent of post-translational modifications? If so, you'll be interested in this comparison of in-solution protein digestion approaches...

    

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