Pharma Science

This application note describes a method for the preparative purification of Ibuprofen and its analogs using the Prominence™ UFPLC designed to improve the efficiency of your workflow.

In this study, a successful micro LC-MS/MS method for the highly sensitive quantitation of desmopressin in human plasma is demonstrated. It shows how the QTRAP^® 6500+ LC MS/MS system with OptiFlow™ Source coupled with a M5 MicroLC system provides...

This application note demonstrates a method for the high-speed analysis of pramipexole following the draft guidance of International Harmonization of Pharmacopoeias. It uses Shimadzu's integrated LC system, the Nexera™ - i MT. 

This study describes in detail an improved immunoaffinity-micro LC-MS/MS workflow for quantifying trastuzumab emtansine in mouse plasma using the SCIEX 6500+ QTRAP^® System with OptiFlow™ Turbo V source and M5 MicroLC System.

This application demonstrates an effective method for the analysis irbesartan using Shimadzu's integrated LC system, the Nexera™ - i MT. 

This study describes the LCMS bioanalysis of antibody drugs using the Fab-selective proteolysis "nSMOL Method" offering an improvement of reaction conditions for automated analyses.

PSS has produced an application note demonstrating a specific workflow in which its PSS WinGPC Software allows for calibration and molar mass determination for Dextran 40, 60 and 70 as stated by United States Pharmacopeia (USP) and European...

This on-demand webinar will discuss Waters® Openlynx™ Open Access Solutions and new workflows designed to streamline the implementation of supercritical fluid chromatography (SFC) technologies focused on supporting Medicinal Chemistry and...

SCiEX has produced a technical note describing an immunoaffinity-high resolution accurate mass assay for the pre-clinical quantification of Trastuzumab in rat plasma.

Find, Identify and Confirm Peptide Catabolites Using MetabolitePilot^TM 2.0 Software and the Advanced Biotransform Solution.

SCIEX has produced a technical note describing metabolite identification of payload species of antibody drug conjugates with noncleavable linkers using MetabolitePilot™ 2.0 software and TripleTOF^® 6600 systems.

Peptide mapping is critical for characterizing protein drugs and monitoring product critical quality attributes (CQAs) in biopharma. Due to the heterogenous nature of protein drugs, comprehensive analytical characterization is required for...