Pharma Science

Speed up your analysis of pharmaceutical impurities with SIFT-MS

Direct MS offers benefits for the analysis of volatile impurities in pharmaceutical products. Interested? If so, why not learn how selected-ion flow-tube mass spectrometry can help...

Sniffing out Parkinson's Disease for Early Diagnosis using GC/MS and Olfactory Detection 

A former nurse, Joy Milne, is using her incredible sense of smell to help researchers develop a method for early detection of Parkinson's disease. Some diseases lead to changes in metabolism and the emission of certain odours specific to the...

HPAE-PAD - A very useful tool for glycan analysis

Looking for analytical advantage with your glycan and glycosylation analysis? If so, then high-performance anion-exchange chromatography with pulsed amperometric detection may well be worth a look...

High-Resolution Sampling 2D-LC for Pharmaceutical Impurity Analysis

Agilent Technologies has produced an application note demonstrating the use of high-resolution (HiRes) sampling 2D-LC for the separation and detection of impurities, exemplified for different isomers of chlorodifluorobenzoic acid at relative...

Achieve Fast Glycan Labelling and Analysis

SCIEX has produced an application note describing the N-glycosylation profiling of carbohydrates associated with therapeutic antibodies for faster, more cost-effective development of biologics.

DAR Analysis of Antibody-Drug Conjugates

Tosoh Bioscience has produced an application note describing drug-to-antibody ratio (DAR) analysis of an antibody-drug conjugate by hydrophobic interaction chromatography (HIC).

Practical HPLC for Biopharmaceuticals – Training Module 1: Isocratic HPLC Basics

Although “small molecule” and “biopolymer” separations have traditionally been considered as separate activities, analysts in the biopharmaceutical industry regularly have to deal with both. Fortunately, the underlying principles of...

Trends in IC for pharmaceutical analysis - expert interview, part 2

This is the second part of our discussion with Dr Jeffrey Rohrer, Director of Applications for ion chromatography (IC) products at Thermo Fisher Scientific for his thoughts on the evolving role of IC in regulated pharmaceutical analysis...

Determination of Leachables in Orally Inhaled and Nasal Drug Products (OINDP) by GC/MS-MS

Shimadzu has produced an application note describing a highly sensitive method for the quantitation of 40 leachables in OINDP products by GC/MS-MS.

New Mass Spectrometer Platform Offers Greater Quantitative Sensitivity, Speed and Reproducibility

New Q Exactive HF-X Orbitrap mass spectrometer enables scientists to advance disease research and drug discovery.

Phospholipid Analysis for Four Types of Mouse Tissues using Triple Quadrupole LC-MS/MS with SimLipid

Shimadzu has produced an application note describing phospholipid analysis for four types of mouse tissues performed by precursor ion scan (PIS) or neutral loss scan (NLS) with a triple quadrupole mass spectrometer.

How can light scattering can improve your GPC/SEC

Learn about the advantages and benefits of light scatttering techniques and how they can help your analysis of polymeric excipients.

     

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