Pharmaceutical Analysis Blog

A short course in the systematic validation of HPLC methods. The validation process is best started with the first injection during method development. We discuss the importance of having an overall plan for the method development / validation /...

The therapeutic potential of biologic modalities has increased, driving an inevitable move toward exploring more complex biotherapeutic molecule classes. As biotherapeutics become more complex, there is still a demand for superior quantification...

Would you like to learn more about the vital role of compendial methods in pharmaceutical analysis and how, by making adjustments to them, laboratory efficiency can be increased and cost decreased? If so, this webinar will provide the answers.

The selection of the proper background electrolyte (BGE) is key to a successful CE method. We first look into the choices for BGE based on our analyte properties. Capillary electrophoresis (CE) is based on migration of charged components in an...

A short course in the systematic validation of HPLC methods. We start by taking an overview of the validation process and review some of the key references that will be useful in setting up a validation process. We also discuss the terminology...

Once a chemical hit is found through a library screening process and verified, the synthetic route is then optimized. This step involves an iterative process of synthesis and reactivity measurements of the new compound(s) to further develop the...

Looking for an effective method for monoclonal antibody analysis? SEC-MS could be the answer...

The capillary electrophoresis (CE)techniques have been around since the 1980s, and commercial instruments available since the end of that decade. So why would we start on such a topic now? There are several indications for a growing interest in...

In previous articles HPTLC (High Performance Thin-Layer Chromatography) applications for a series of medicinal plants, such as Ginkgo, Hypericum or Ginseng, have been presented.

In convergence chromatography (CC), the modes of interaction between the stationary phase and the solute are numerous, including hydrogen bonding, hydrophobic interactions, dipolar and polarizability interactions and solute partitioning [1]....

Looking for new and improved technologies to advance your peptide mapping strategies? Do you want to overcome automation problems with your therapeutic protein workflows? If so, signup for this educational presentation...

SUCCESSFUL CHROMATOGRAPHY STARTS AT THE BEGINNING

Understanding the basics of any chromatographic technique is the first step towards achieving your analytical goals and allowing correct decision making and effective pharmaceutical method...