Pharmaceutical Analysis

In this application note purification of a single-stranded RNA oligonucleotide by ion pair reversed-phase HPLC is demonstrated, achieving > 99% pure fraction pool with a yield of > 56%.

The recent years have witnessed the emergence of nitrosamines as a serious contaminant group in APIs from the sartan family. In this article, from Issue 11 of the Analytix Reporter, produced by Merck, a GC-MS method to determine nitrosamines in...

This eBook contains a selection of application notes relevant for pharmaceutical and biopharmaceutical analysis using HPLC / (U)HPLC or LC-MS/MS.

Separation Science, in collaboration with Shimadzu, offers a series of application notes exploring the latest and most up-to-date solutions for COVID-19 drug analysis. Click below to download your personal copies.

While Asia’s pharmaceutical businesses cope with the changes in operating environments, the scientific community, involving local and international scientists, chemists and laboratory professionals, needs to continue to strengthen and grow through...

Would you like to learn more about the vital role of compendial methods in pharmaceutical analysis and how, by making adjustments to them, laboratory efficiency can be increased and cost decreased? If so, this on-demand webinar will provide the...

Do you currently experience a lack of reliable methods for the quantification of submicron (0.1 to 1 mm) protein aggregates? Would you like to learn more about how field-flow fractionation and light scattering are suitable techniques for studying...

Do you encounter challenges with polymer characterization and would like to learn more about cutting-edge technology that can help identify and overcome any shortfalls of your current techniques? If so, this presentation from Separation Science, in...

SCiEX has produced a technical note describing an immunoaffinity-high resolution accurate mass assay for the pre-clinical quantification of Trastuzumab in rat plasma.

Find, Identify and Confirm Peptide Catabolites Using MetabolitePilot^TM 2.0 Software and the Advanced Biotransform Solution.

SCIEX has produced a technical note describing metabolite identification of payload species of antibody drug conjugates with noncleavable linkers using MetabolitePilot™ 2.0 software and TripleTOF^® 6600 systems.

In this on-demand presentation, some examples of applications of different NMR structural techniques with cases from late lead optimization and preclinical development phase will be presented and discussed. Focus will be given also to the combined...

Attend this on-demand webinar by Carla Marchioro and you will learn how structural techniques contribute to drug discovery and development. This will be further explained through application examples.

SCIEX introduces its OptiFlow Quant Solution providing microflow sensitivity and analytical flow usability. Learn how to enhance your sensitivity for challenging analytes such as peptides, mAbs and ADCs.

Attend this on-demand webinar and learn about workflows involved in pharmaceutical impurity analysis and API stability studies, and how to deliver confidence in the identification of unknown impurities...