--- title: Pharmaceutical Analysis Blog | Separation Science in collaboration with Shimadzu (2) description: SHIMADZU (http://www.shimadzu.com/an/) aims to be preeminent in science, so as to provide a safe and healthy lifestyle, and to bequeath this beautiful earth to future generations. (2) --- - [Home](https://www.sepscience.com/pharma) - [Separation Science](https://www.sepscience.com) - [日本語](https://www.sepscience.com/japan) - [Chromatography Forum](http://www.chromforum.org/) - [Analytical Training Solutions](https://www.analytical-training-solutions.com) - [Contact Us](https://www.sepscience.com/eclipse-business-media/contact-us/) - [Subscribe for free](https://www.sepscience.com/subscribe/) [![Separation Science](https://blog.sepscience.com/hubfs/Sepscience_Dec2016/images/-resized-strch-SepSci_WebHeader_v3.png)](https://www.sepscience.com/) - [Food](https://www.sepscience.com/food) - [Enviro](https://www.sepscience.com/enviro) - [Pharma](https://www.sepscience.com/pharma) - [Bio Clinical](https://www.sepscience.com/bioclinical) - [LC](https://www.sepscience.com/lc) - [GC](https://www.sepscience.com/gc) - [MS](https://www.sepscience.com/ms) - [Methods & Applications](https://www.sepscience.com/methods-and-applications/) - [Webinars & eSeminars](https://www.sepscience.com/webinars-and-eseminars/) - [Videos & Tutorials](https://www.sepscience.com/videos-and-tutorials/) - [Home](https://www.sepscience.com/) - [Get in Touch with Us](https://www.sepscience.com/) - [Home](https://www.sepscience.com/pharma) - Pharmaceutical Analysis[Pharmaceutical Analysis](https://blog.sepscience.com/pharmascience) - [Pharmaceutical Analysis Blog](https://blog.sepscience.com/pharmascience/author/separation-science-in-collaboration-with-shimadzu) # Pharmaceutical Analysis ## Separation Science in collaboration with Shimadzu ![](https://blog.sepscience.com/hubfs/Companies/Shimadzu/Shimadzu.png) SHIMADZU (http://www.shimadzu.com/an/) aims to be preeminent in science, so as to provide a safe and healthy lifestyle, and to bequeath this beautiful earth to future generations. ### Recent Posts ### [FTIR Spectrophotometers to Simplify Analysis and Provide Outstanding Expandability](https://blog.sepscience.com/pharmascience/ftir-spectrophotometers-to-simplify-analysis-and-provide-outstanding-expandability) Shimadzu has introduced its [IRSpirit series](https://www.shimadzu.eu/ready-to-run) of Fourier Transform Infrared (FTIR) spectrophotometers, the IRSpirit-T and IRSpirit-L compact-sized models, designed to simplify analysis and provide outstanding expandability. [Read More](https://blog.sepscience.com/pharmascience/ftir-spectrophotometers-to-simplify-analysis-and-provide-outstanding-expandability) ### [Screening Analysis of Highly Polar Doping Agents in Urine Using 2D LC-MS/MS](https://blog.sepscience.com/pharmascience/screening-analysis-of-highly-polar-doping-agents-in-urine-using-2d-lc-ms/ms) Shimadzu has produced an application note highlighting 2D LC-MS/MS for the simultaneous analysis of highly polar doping agents and adrenergic agents. Download the full application note to see which compounds can be detected. ... [Read More](https://blog.sepscience.com/pharmascience/screening-analysis-of-highly-polar-doping-agents-in-urine-using-2d-lc-ms/ms) ### [Determination of Leachables in Orally Inhaled and Nasal Drug Products (OINDP) by GC/MS-MS](https://blog.sepscience.com/pharmascience/determination-of-leachables-in-orally-inhaled-and-nasal-drug-products-oindp-by-gc/msms) Shimadzu has produced an application note describing a highly sensitive method for the quantitation of 40 leachables in OINDP products by GC/MS-MS. [Read More](https://blog.sepscience.com/pharmascience/determination-of-leachables-in-orally-inhaled-and-nasal-drug-products-oindp-by-gc/msms) ### [Phospholipid Analysis for Four Types of Mouse Tissues using Triple Quadrupole LC-MS/MS with SimLipid](https://blog.sepscience.com/pharmascience/phospholipid-analysis-for-four-types-of-mouse-tissues-using-triple-quadrupole-lc-ms/ms-with-simlipid) Shimadzu has produced an application note describing phospholipid analysis for four types of mouse tissues performed by precursor ion scan (PIS) or neutral loss scan (NLS) with a triple quadrupole mass spectrometer. [Read More](https://blog.sepscience.com/pharmascience/phospholipid-analysis-for-four-types-of-mouse-tissues-using-triple-quadrupole-lc-ms/ms-with-simlipid) ### [High-Sensitivity Analysis of Residual Solvents in Drug Products - USP <467> Residual Solvents Procedure A](https://blog.sepscience.com/pharmascience/high-sensitivity-analysis-of-residual-solvents-in-drug-products-usp-467-residual-solvents-procedure-a) Shimadzu has produced an application note presenting data obtained from Class 1 and Class 2 standard solutions, in accordance with *Water-Soluble Articles, Procedure A*, in USP <467> Residual Solvents. [Read More](https://blog.sepscience.com/pharmascience/high-sensitivity-analysis-of-residual-solvents-in-drug-products-usp-467-residual-solvents-procedure-a) ### [High Speed LC Analysis of Pharmaceutical Impurities in Compliance with European Pharmacopoeia](https://blog.sepscience.com/pharmascience/high-speed-lc-analysis-of-pharmaceutical-impurities-in-compliance-with-european-pharmacopoeia) Shimadzu has produced an application note describing a newly developed method for the high-speed analysis of pharmaceuticals and related substances in compliance with *European Pharmacopoeia* using the Nexera-i MT. [Read More](https://blog.sepscience.com/pharmascience/high-speed-lc-analysis-of-pharmaceutical-impurities-in-compliance-with-european-pharmacopoeia) ### [LC-MS/MS Bioanalysis of Trastuzumab Using Fab-Selective Proteolysis ‘nSMOL’](https://blog.sepscience.com/pharmascience/lc-ms/ms-bioanalysis-of-trastuzumab-using-fab-selective-proteolysis-nsmol) Shimadzu has produced an application note demonstrating how the LC-MS/MS bioanalysis of antibody drugs has been significantly simplified by this unique nSMOL technology. In this application, the analysis of Trastuzumab is discussed.  [Read More](https://blog.sepscience.com/pharmascience/lc-ms/ms-bioanalysis-of-trastuzumab-using-fab-selective-proteolysis-nsmol) ### [Analysis of Polysorbate 80 in IgG Aqueous Solution by Online SPE Using Shim-pack MAYI Column – Part 2](https://blog.sepscience.com/pharmascience/analysis-of-polysorbate-80-in-igg-aqueous-solution-by-online-spe-using-shim-pack-mayi-column-part2) Continued from the previous application (Part 1), Shimadzu has produced an application note demonstrationg how the same online-SPE system using Shim-pack MAYI-ODS was now deployed for the detection of various impurities contained in polysorbate 80... [Read More](https://blog.sepscience.com/pharmascience/analysis-of-polysorbate-80-in-igg-aqueous-solution-by-online-spe-using-shim-pack-mayi-column-part2) ### [Analysis of Polysorbate 80 in IgG Aqueous Solution by Online SPE Using Shim-pack MAYI Column – Part 1](https://blog.sepscience.com/pharmascience/analysis-of-polysorbate-80-in-igg-aqueous-solution-by-online-spe-using-shim-pack-mayi-column-part-1) Shimadzu has produced an application note demonstrating how the analysis of polysorbate 80 in IgG aqueous solution is simplified using an online-SPE system. [Read More](https://blog.sepscience.com/pharmascience/analysis-of-polysorbate-80-in-igg-aqueous-solution-by-online-spe-using-shim-pack-mayi-column-part-1) ### [Detection of Protein Aggregates using a Mass Spectrometric Approach](https://blog.sepscience.com/pharmascience/detection-of-protein-aggregates-using-a-mass-spectrometric-approach) Shimadzu has produced an application note describing the detection of protein aggregates using a mass spectrometric approach with versatile MALDI-TOF instrumentation. [Read More](https://blog.sepscience.com/pharmascience/detection-of-protein-aggregates-using-a-mass-spectrometric-approach) ### [Fast and Sensitive Method for the Separation and Quantitation of Oxysterol Compounds](https://blog.sepscience.com/pharmascience/fast-and-sensitive-method-for-the-separation-and-quantitation-of-oxysterol-compounds) Shimadzu has produced an application note presenting a fast, sensitive LC-MS/MS method for the separation and quantitation of oxysterol compounds using LC-MS/MS. [Read More](https://blog.sepscience.com/pharmascience/fast-and-sensitive-method-for-the-separation-and-quantitation-of-oxysterol-compounds) ### [Cleaning Validation for Pharmaceutical Manufacturing by Online SFE-SFC](https://blog.sepscience.com/pharmascience/cleaning-validation-for-pharmaceutical-manufacturing-by-online-sfe-sfc) Shimadzu has produced a paper that evaluates the application of a novel on-line supercritical fluid extraction/chromatography system for cleaning validation in pharmaceutical manufacturing.The benefits of online SFE/SFC are shown to be data... 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