Pharma Science

Detection of Sibutramine in Slimming Products by HPTLC and Confirmation by HPTLC-MS

CAMAG has produced an application note describing the HPTLC methodology to identify sibutramine in herbal weight loss products.

Effective Cannabis Testing with HPTLC

CAMAG has produced an application note describing the different possibilities for Cannabis testing by HPTLC.

Separation of Amphetamine Enantiomers by SFC

Agilent Technologies has produced an application note demonstrating the separation of enantiomers of amphetamines and their positional isomers on chiral phase columns using SFC with mass spectrometry.

Take Your Quantitation Studies to a New Level

SCIEX introduces its OptiFlow Quant Solution providing microflow sensitivity and analytical flow usability. Learn how to enhance your sensitivity for challenging analytes such as peptides, mAbs and ADCs.

Monitoring Antibody Oxidation at The Subunit Level

SCIEX has produced an application note demonstrating how to monitor biotherapeutic oxidation levels in a simple and automated way using the X500B QTOF system and powerful BioPharmaView™ Software.

Routine Workflow for Comparability Assessment of Protein Biopharmaceuticals using High-resolution LC-MS

SCIEX has produced an application note demonstrating using a reproducible and robust method for analysing intact biotherapeutic proteins on the X500B QTOF System with automated batch processing using BioPharmaView™ software.

Comparative Peptide Mapping Between Two Manufacturers of Trastuzumab 

SCIEX has produced an application note describing a simple and rapid methodology to characterize and quantify differences between biotherapeutic batches, using high-resolution peptide mapping by LC-MS.

 

Screening Analysis of Highly Polar Doping Agents in Urine Using 2D LC-MS/MS

Shimadzu has produced an application note highlighting 2D LC-MS/MS for the simultaneous analysis of highly polar doping agents and adrenergic agents. Download the full application note to see which compounds can be detected.

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Determination of Leachables in Orally Inhaled and Nasal Drug Products (OINDP) by GC/MS-MS

Shimadzu has produced an application note describing a highly sensitive method for the quantitation of 40 leachables in OINDP products by GC/MS-MS.

High-Sensitivity Analysis of Residual Solvents in Drug Products - USP <467> Residual Solvents Procedure A

Shimadzu has produced an application note presenting data obtained from Class 1 and Class 2 standard solutions, in accordance with Water-Soluble Articles, Procedure A, in USP <467> Residual Solvents.

High Speed LC Analysis of Pharmaceutical Impurities in Compliance with European Pharmacopoeia

Shimadzu has produced an application note describing a newly developed method for the high-speed analysis of pharmaceuticals and related substances in compliance with European Pharmacopoeia using the Nexera-i MT.

Current Methodologies for Drugs of Abuse Urine Testing

Biotage has produced a white paper examining a number of aspects of sample preparation and their impact on the success of subsequent LC-MS/MS analysis of broad urine panels.

     

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