Once a chemical hit is found through a library screening process and verified, the synthetic route is then optimized. This step involves an iterative process of synthesis and reactivity measurements of the new compound(s) to further develop the...
In convergence chromatography (CC), the modes of interaction between the stationary phase and the solute are numerous, including hydrogen bonding, hydrophobic interactions, dipolar and polarizability interactions and solute partitioning [1]....
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