Pharmaceutical Analysis

Released N-glycan analysis of a therapeutic antibody

N-glycan analysis is critical to the characterization of therapeutic monoclonal antibodies. In this article, from Issue 9 of the Analytix Reporter, produced by Merck, a BIOshell™ Glycan HPLC column is used to analyze Cetuximab (Erbitux®) N-glycans...

Advanced Methods for Biomolecule Analysis

Separation Science, in collaboration with Agilent, offers an eBook covering advanced methods for the analysis of biomolecules, including monoclonal antibodies and biotherapeutics. Glycan and glycosylation analysis, charge variant analysis and...

HPLC-DAD analysis of nucleotides

Phosphorylated compounds such as nucleotides are known to interact with stainless steel components leading to recovery issues in HPLC and LC/MS. Instrument and column inertness ensure successful analysis. Discover more about the bio-inert analysis...

HPAE-PAD - A very useful tool for glycan analysis

Looking for analytical advantage with your glycan and glycosylation analysis? If so, then high-performance anion-exchange chromatography with pulsed amperometric detection may well be worth a look...

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