Pharma Science

Screening Analysis of Highly Polar Doping Agents in Urine Using 2D LC-MS/MS

Shimadzu has produced an application note highlighting 2D LC-MS/MS for the simultaneous analysis of highly polar doping agents and adrenergic agents. Download the full application note to see which compounds can be detected.


Determination of Leachables in Orally Inhaled and Nasal Drug Products (OINDP) by GC/MS-MS

Shimadzu has produced an application note describing a highly sensitive method for the quantitation of 40 leachables in OINDP products by GC/MS-MS.

High-Sensitivity Analysis of Residual Solvents in Drug Products - USP <467> Residual Solvents Procedure A

Shimadzu has produced an application note presenting data obtained from Class 1 and Class 2 standard solutions, in accordance with Water-Soluble Articles, Procedure A, in USP <467> Residual Solvents.

High Speed LC Analysis of Pharmaceutical Impurities in Compliance with European Pharmacopoeia

Shimadzu has produced an application note describing a newly developed method for the high-speed analysis of pharmaceuticals and related substances in compliance with European Pharmacopoeia using the Nexera-i MT.

Current Methodologies for Drugs of Abuse Urine Testing

Biotage has produced a white paper examining a number of aspects of sample preparation and their impact on the success of subsequent LC-MS/MS analysis of broad urine panels.

Proof of Equivalency for the Analysis of Beta-Blockers

Agilent Technologies has produced an application note that shows the seamless transfer of a method for the analysis of beta-blockers from an Agilent 1260 Infinity LC to an Agilent 1260 Infinity II LC. It proves that equivalent results in terms of...

High-Throughput LC/MS/MS Method for the Analysis of Pain Management Drugs

PerkinElmer has produced an effective LC/MS/MS method providing a fast, accurate and reproducible solution for the analysis of pain management drugs.

Proof of Equivalency for the Analysis of Local Anesthetics

Agilent Technologies has produced an application note proving equivalency of the Agilent 1200 Series Binary LC and the Agilent 1260 Infinity II LC for the analysis of local anesthetics.

LC Analysis of Vitamin D Epimers on Raptor FluoroPhenyl Columns

Restek has produced an application note demonstrating how the Raptor FluoroPhenyl column is a good choice for vitamin D analysis as opposed to C18 columns.

A Modified QuEChERS Approach for the Extraction of Common Prescription and Illicit Drugs from Liver

UCT has produced an application note outlining a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) technique that has been optimized to extract common prescription and illicit drugs from liver prior to analysis by LC-MS/MS.

Profiling the Distribution of N-Glycosylation in Therapeutic Antibodies

SCIEX has produced an application note demonstrating how a comprehensive MS/MS analysis of glycopeptides can be achieved by targeting the known nature of the glycosylation structures using the QTRAP® 6500 system. 

Separation of Statistic MMA-MAA Copolymers using Gradient SEC

PSS has produced an application note describing how gradient SEC is the method of choice for characterizing statistic copolymers of methyl methacrylate (MMA) and methacrylic acid (MAA) that are widely used in pharmaceutical applications. 


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