Pharmaceutical Analysis Blog

Why CE (Capillary Electrophoresis)?

The capillary electrophoresis (CE)techniques have been around since the 1980s, and commercial instruments available since the end of that decade. So why would we start on such a topic now? There are several indications for a growing interest in...

HPTLC application for Passiflora incarnata

In previous articles HPTLC (High Performance Thin-Layer Chromatography) applications for a series of medicinal plants, such as Ginkgo, Hypericum or Ginseng, have been presented.

Practical Considerations for Achiral Analysis of Pharmaceutical Compounds Using Convergence Chromatography

In convergence chromatography (CC), the modes of interaction between the stationary phase and the solute are numerous, including hydrogen bonding, hydrophobic interactions, dipolar and polarizability interactions and solute partitioning [1]....

Effective analysis of residual solvents according to USP <467> method using a static headspace autosampler

Thermo Fisher Scientific has produced an application note with the goal of evaluating the performance of a new Thermo Scientific™ TriPlus™ 500 Gas Chromatography Headspace Autosampler for the determination of residual solvent content in...

Fundamentals and applications of agarose resins in SEC of proteins

Want to read a great introduction to SEC for protein analysis, and the advantages of new-generation agarose columns - then take a look at this new white paper from GE Healthcare.

Benefits of field-flow fractionation and light scattering in protein aggregation

Do you currently experience a lack of reliable methods for the quantification of submicron (0.1 to 1 mm) protein aggregates? Would you like to learn more about how field-flow fractionation and light scattering are suitable techniques for studying...

Perform absolute characterization of polymeric excipients

Do you encounter challenges with polymer characterization and would like to learn more about cutting-edge technology that can help identify and overcome any shortfalls of your current techniques? If so, this presentation from Separation Science,...

ISPPP 2019: International Symposium on the Purification of Proteins, Peptides and Polynucleotides

ISPPP (International Symposium on the Separation of Proteins, Peptides and Polynucleotides) takes place 10-12 July 2019 in Baltimore. Come see the Latest Innovations in Technologies Critical in Clinical and Biopharmaceutical Research.

PREP 2019 Symposium and Exhibit on Preparative and Process Chromatography

PREP 2019 takes place 7-10 July this year in Baltimore - find out more about what's going on and why you should think about attending... PREP 2019 is the longest running, most recognized international scientific conference and exposition in the...

Discover a method for the preparative purification of Ibuprofen

This application note describes a method for the preparative purification of Ibuprofen and its analogs using the Prominence™ UFPLC designed to improve the efficiency of your workflow.

Sub-picogram level quantitation of desmopressin

In this study, a successful micro LC-MS/MS method for the highly sensitive quantitation of desmopressin in human plasma is demonstrated. It shows how the QTRAP® 6500+ LC MS/MS system with OptiFlow™ Source coupled with a M5 MicroLC system provides...

High-speed analysis of pramipexole that meets regulatory compliance

This application note demonstrates a method for the high-speed analysis of pramipexole following the draft guidance of International Harmonization of Pharmacopoeias. It uses Shimadzu's integrated LC system, the Nexera™ - i MT. 

    

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