Pharmaceutical Analysis Blog

Updating HPLC compendial methods for improved pharmaceutical analysis

Would you like to learn more about the vital role of compendial methods in pharmaceutical analysis and how, by making adjustments to them, laboratory efficiency can be increased and cost decreased? If so, this webinar will provide the answers.

Method Development in Capillary Electrophoresis (CE): Selecting your Background Electrolyte

The selection of the proper background electrolyte (BGE) is key to a successful CE method. We first look into the choices for BGE based on our analyte properties. Capillary electrophoresis (CE) is based on migration of charged components in an...

Principles of HPLC Validation - Training Module 1: Introduction

A short course in the systematic validation of HPLC methods. We start by taking an overview of the validation process and review some of the key references that will be useful in setting up a validation process. We also discuss the terminology...

Reaction Monitoring with UltraPerformance Convergence Chromatography

Once a chemical hit is found through a library screening process and verified, the synthetic route is then optimized. This step involves an iterative process of synthesis and reactivity measurements of the new compound(s) to further develop the...

Analysis of a bispecific monoclonal antibody with SEC-MS

Looking for an effective method for monoclonal antibody analysis? SEC-MS could be the answer...

Why CE (Capillary Electrophoresis)?

The capillary electrophoresis (CE)techniques have been around since the 1980s, and commercial instruments available since the end of that decade. So why would we start on such a topic now? There are several indications for a growing interest in...

HPTLC application for Passiflora incarnata

In previous articles HPTLC (High Performance Thin-Layer Chromatography) applications for a series of medicinal plants, such as Ginkgo, Hypericum or Ginseng, have been presented.

Practical Considerations for Achiral Analysis of Pharmaceutical Compounds Using Convergence Chromatography

In convergence chromatography (CC), the modes of interaction between the stationary phase and the solute are numerous, including hydrogen bonding, hydrophobic interactions, dipolar and polarizability interactions and solute partitioning [1]....

Easy characterisation workflows in therapeutic protein analysis

Looking for new and improved technologies to advance your peptide mapping strategies? Do you want to overcome automation problems with your therapeutic protein workflows? If so, signup for this educational presentation...

The keys to understanding isocratic HPLC

SUCCESSFUL CHROMATOGRAPHY STARTS AT THE BEGINNING

Understanding the basics of any chromatographic technique is the first step towards achieving your analytical goals and allowing correct decision making and effective pharmaceutical method...

The role of light scattering in biopharmaceutical formulation development

Are you involved in biopharmaceutical research? Would you like to find out more about the role of light scattering and associated techniques in characterizing biological molecules? This presentation from Separation Science, in collaboration with...

Effective analysis of residual solvents according to USP <467> method using a static headspace autosampler

Thermo Fisher Scientific has produced an application note with the goal of evaluating the performance of a new Thermo Scientific™ TriPlus™ 500 Gas Chromatography Headspace Autosampler for the determination of residual solvent content in...

    

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