Pharma Science

Adulteration of St. John’s Wort Products: An HPTLC-MS Investigation.

CAMAG has produced an application note describing an HPTLC methodology for the identification of SJW and a simple test for adulteration.

Detection of Steroids and SARMs using HPTLC

CAMAG has produced an application note describing a simple and rapid HPTLC screening method for steroids and selective androgen receptor modulators (SARMs) in bodybuilding supplements. 

Achieve high-throughput LC/MS purification of pharmaceutical impurities

Agilent Technologies has produced an application note describing the separation and purification of acetaminophen (paracetamol) and six common impurities listed in the European and United States Pharmacopoeias.

Doubling chromatographic throughput using dual LC for pharmaceutical analysis

Thermo Fisher Scientific has produced an application note describing a novel Dual LC workflow, which provides a unique concept by using two separated flow paths in one system. It shows how the Thermo Scientific Vanquish Duo system for Dual LC...

How to analyse small pharmaceuticals and peptide mixtures using chemically stable merged inorganic/organic silica material

Kromasil has produced an application note demonstrating how, by using merged inorganic/organic silica materials with newly developed C8, C18 or phenyl hexyl phases, it is possible to use a stationary phase with a wider pH range. 

Effective Determination of Diclofenac and Its Related Compounds using RP-HPLC-ICP-QQQ

Agilent Technologies has produced an application note describing the quantitative determination of the drug diclofenac and its related compounds in human plasma. Compounds were quantified based on measurement of the Cl heteroatom using...

Separation of Amphetamine Enantiomers by SFC

Agilent Technologies has produced an application note demonstrating the separation of enantiomers of amphetamines and their positional isomers on chiral phase columns using SFC with mass spectrometry.

[On-Demand Webinar] Accelerating Large Molecule LC-MS Method Development

Rapid development of sensitive and selective peptide bioanalytical methods are required to support the expanding protein component of pharmaceutical companies’ drug pipeline. Choosing the best MRM for a large molecule peptide or protein is a...

Take Your Quantitation Studies to a New Level

SCIEX introduces its OptiFlow Quant Solution providing microflow sensitivity and analytical flow usability. Learn how to enhance your sensitivity for challenging analytes such as peptides, mAbs and ADCs.

Confident pharmaceutical impurity profiling using high-res mass spec

Attend this on-demand webinar and learn about workflows involved in pharmaceutical impurity analysis and API stability studies, and how to deliver confidence in the identification of unknown impurities...

Monitoring Antibody Oxidation at The Subunit Level

SCIEX has produced an application note demonstrating how to monitor biotherapeutic oxidation levels in a simple and automated way using the X500B QTOF system and powerful BioPharmaView™ Software.

Routine Workflow for Comparability Assessment of Protein Biopharmaceuticals using High-resolution LC-MS

SCIEX has produced an application note demonstrating using a reproducible and robust method for analysing intact biotherapeutic proteins on the X500B QTOF System with automated batch processing using BioPharmaView™ software.