Liquid Chromatography

Separation Science in collaboration with the life science business of Merck KGaA, Darmstadt, Germany

Recent Posts

Karl Fischer Titration: Three Webinars and a Roundtable

Karl Fischer titration is still the most used, most accurate, and fastest method to determine water content in all kinds of sample matrices.

Tips & Tricks for Thin-Layer Chromatography

This article from Issue 14 of the Analytix Reporter discusses thin-layer chromatography (TLC), a fast, easy-to-use, cost-efficient, and highly versatile separation technique for qualitative and quantitative analysis. It describes some of the key...

HPLC Tips & Tricks: Optimizing Injection Volume

How much sample can you inject into your HPLC system or chosen method? What are the limitations and boundaries? Read more in this edition of 'Tips & Tricks' in Issue 13 of the Analytix Reporter for an overview and advice on injection volumes in HPLC.

Titripac® Sustainable Packaging for Ready-to-Use Certipur® pH Buffers

This article from Issue 13 of the Analytix Reporter shows how the hermetically sealed Titripac® packaging for Certipur® pH buffer solutions prevents contamination and ensures stability and quality of the buffer solutions. Find more about the...

The Carbon Enigma: Material Fundamentals and Retention Properties Of Porous Graphitic Carbon Stationary Phases

As a follow up to the Analytix Reporter Issue 10 article, “Applications Employing New 2.7 μm Porous Graphitic Carbon Particles for U/HPLC”, we explore here, in a shortened review from Issue 13, the more fundamental and theoretical topics concerning...

Synthetic carbon separation media for procss and preparative chromatography

Discover the features, advantages and benefits of synthetic carbon separation media in both liquid and gas purifications and how they bring value to a wide range of LPLC applications for both small and large molecule separations by attending this...

Tips & Tricks: Karl Fischer Titration

Some samples do not easily release water for Karl Fischer determinations. So, what are the workable options in such instances? This article from Issue 12 of the Analytix Reporter, produced by Merck, discusses the steps that can be taken to release...

HPLC Tips & Tricks: Mobile Phase Preparation - Buffers

The mobile phase in HPLC strongly influences chromatographic separations. Its preparation can prove to be a source of trouble for a method, if not done correctly and consistently. Part two of this series on mobile phase preparation focuses on...

HPLC Products: The Best Choice for Any LC Instrument

In this article from Issue 11 of the Analytix Reporter, produced by Merck, learn about the Supelco® HPLC columns portfolio and the best practices for connecting the column to any instrument to get maximum performance.

Stable Isotope-Labeled Amino Acid Mixes

This article from Issue 11 of the Analytix Reporter, produced by Merck, describes the addition of two new certified solution mixtures of labeled amino acids to the company's portfolio. These certified reference material (CRM) mixes are suitable for...

How to Increase The Cost Effectiveness for HPLC Separations of Challenging and Matrix-rich Samples

In this on-demand webinar, the potential for cost and time savings by increasing lab productivity with faster separations and column materials providing very high matrix tolerance is discussed. For further details and to register, click below.

Continue to Improve your Titration Process with New Tips and Tricks

Would you like to learn some further tips and tricks for optimizing the titration process? If so, watch this on-demand webinar. For further details and to register, click below.

HPLC tips & tricks - increase your HPLC/UHPLC method sensitivity

The sensitivity of a chromatographic method might be described by its limit of detection (LOD). LOD is usually defined as the minimum detectable amount or concentration of a component that can be reliably detected using a given analytical method....

SPME adsorbent fibers on Nitinol core for improved fiber reproducibility

Adsorbent SPME fibers with Carboxen® or divinylbenzene (DVB) coatings on a Nitinol core have been introduced. In the provided study, the Nitinol core fibers show an improved reproducibility and mechanical stability vs. their predecessors on fused...

Applications of Newly Developed 2.7 μm Porous Graphitic Carbon Particles in U/HPLC

This article from Issue 10 of the Analytix Reporter, produced by Merck, describes a unique stationary phase for improved retention and analysis of polar compounds and examples of its applications in food and clinical analysis.

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