Liquid Chromatography

How much sample can you inject into your HPLC system or chosen method? What are the limitations and boundaries? Read more in this edition of 'Tips & Tricks' in Issue 13 of the Analytix Reporter for an overview and advice on injection volumes in HPLC.

This article from Issue 13 of the Analytix Reporter shows how the hermetically sealed Titripac^® packaging for Certipur^® pH buffer solutions prevents contamination and ensures stability and quality of the buffer solutions. Find more about the...

As a follow up to the Analytix Reporter Issue 10 article, “Applications Employing New 2.7 μm Porous Graphitic Carbon Particles for U/HPLC”, we explore here, in a shortened review from Issue 13, the more fundamental and theoretical topics concerning...

Some samples do not easily release water for Karl Fischer determinations. So, what are the workable options in such instances? This article from Issue 12 of the Analytix Reporter, produced by Merck, discusses the steps that can be taken to release...

The mobile phase in HPLC strongly influences chromatographic separations. Its preparation can prove to be a source of trouble for a method, if not done correctly and consistently. Part two of this series on mobile phase preparation focuses on...

In this article from Issue 11 of the Analytix Reporter, produced by Merck, learn about the Supelco^® HPLC columns portfolio and the best practices for connecting the column to any instrument to get maximum performance.

This article from Issue 11 of the Analytix Reporter, produced by Merck, describes the addition of two new certified solution mixtures of labeled amino acids to the company's portfolio. These certified reference material (CRM) mixes are suitable for...

The sensitivity of a chromatographic method might be described by its limit of detection (LOD). LOD is usually defined as the minimum detectable amount or concentration of a component that can be reliably detected using a given analytical method....

Adsorbent SPME fibers with Carboxen^® or divinylbenzene (DVB) coatings on a Nitinol core have been introduced. In the provided study, the Nitinol core fibers show an improved reproducibility and mechanical stability vs. their predecessors on fused...

This article from Issue 10 of the Analytix Reporter, produced by Merck, describes a unique stationary phase for improved retention and analysis of polar compounds and examples of its applications in food and clinical analysis.

The mobile phase in HPLC strongly influences the chromatographic separation. Its preparation can be a source of trouble for a method, if not done correctly and consistently. This article provides some suggestions and practical tips for the mobile...