Liquid Chromatography

HPLC tips & tricks - increase your HPLC/UHPLC method sensitivity

The sensitivity of a chromatographic method might be described by its limit of detection (LOD). LOD is usually defined as the minimum detectable amount or concentration of a component that can be reliably detected using a given analytical method....

SPME adsorbent fibers on Nitinol core for improved fiber reproducibility

Adsorbent SPME fibers with Carboxen® or divinylbenzene (DVB) coatings on a Nitinol core have been introduced. In the provided study, the Nitinol core fibers show an improved reproducibility and mechanical stability vs. their predecessors on fused...

Applications of Newly Developed 2.7 μm Porous Graphitic Carbon Particles in U/HPLC

This article from Issue 10 of the Analytix Reporter, produced by Merck, describes a unique stationary phase for improved retention and analysis of polar compounds and examples of its applications in food and clinical analysis.

HPLC Tips & Tricks - Mobile Phase Preparation

The mobile phase in HPLC strongly influences the chromatographic separation. Its preparation can be a source of trouble for a method, if not done correctly and consistently. This article provides some suggestions and practical tips for the mobile...

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