Liquid Chromatography Blog

Implementing Robustness Testing for HPLC Methods

In this article the selection of appropriate robustness factors and factor levels relating to the mobile phase will be discussed and in particular, the volume fraction of the organic solvent in the mobile phase for reversed phase HPLC.

Advanced LC systems that even support remote working

Shimadzu has announced the release of its “Advanced i-Series” liquid chromatographs meeting user demands for analysing a large number of samples or quickly re-processing data even when working from home.

Particle technologies and their benefits in chromatographic separations

In this on-demand webinar, the advantages of the ACQUITY PREMIER columns are highlighted and the various particle technologies and their benefits in chromatographic separations discussed. Register for the on-demand webinar and see what you've...

How to make the most of your LC system

Would you like to learn some useful tips for preventive maintenance of your LC system and know what to look out for to keep it running at optimal performance? If so, this upcoming webinar from Separation Science, in collaboration with Agilent,...

High-resolution and high-speed simultaneous analysis of regulated UV-adsorbents in cosmetics

This application note provides details of LC conditions and columns to achieve high resolution and high-speed analysis of UV-absorbents using an SPP column.

What's New at the Largest Liquid-Phase Separations Conference in the World

Mark your calendar to attend HPLC 2020 on June 20-25, 2020 in beautiful San Diego, CA, USA along the dramatic Pacific coastline. The HPLC conference will celebrate its 50th edition in 2020, and has grown to become the largest and most visible...

Better prep for multi-sampling processing

Shimadzu has announced the release of its new Nexera Prep Series Preparative Purification Liquid Chromatograph (LC). It provides better prep processes for extraction of target compounds and impurities during drug discovery in the pharmaceutical...

Groundbreaking LC technology to merge ease-of-use and peace-of-mind

Shimadzu's latest issue covers selected analytical applications as well as the latest product information. From groundbreaking LC technology, trace detection of sulfur compounds with SCD and a 20 year anniversary, there is a wealth of information...

Fundamentals of HPLC – Self-paced Online Training

Covers the essentials that every scientist needs in order to make effective use of liquid chromatography instrumentation. You should take this course if you are new to HPLC, or do you supervise new users of HPLC.

HILIC & MS

The separation power of HPLC combined with the very high sensitivity and selectivity of MS detection is widely used to develop analytical methods that are required to achieve ultra-low detection and quantification limits. Examples of such...

Sample Solvent in HILIC

The sample solvent, also called dissolution solvent or injection solvent, is the solvent used to prepare the solution in which the compound to be analysed by HPLC is dissolved. The choice of the sample solvent is fundamental for a successful...

Column Equilibration in HILIC

It is matter of fact that the samples most chromatographers have to face are rather complex for sample number and compound variety. In these situations, gradient elution is largely preferred for the separation of analytes with different retention...

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