--- title: Pharmaceutical Analysis Blog | Methods & Applications (4) description: Methods & Applications | Webinars, methods, application notes, eBooks by Separation Science for pharmaceutical analysis users of chromatography and mass spectrometry. (4) --- - [Home](https://www.sepscience.com/pharma) - [Separation Science](https://www.sepscience.com) - [日本語](https://www.sepscience.com/japan) - [Chromatography Forum](http://www.chromforum.org/) - [Analytical Training Solutions](https://www.analytical-training-solutions.com) - [Contact Us](https://www.sepscience.com/eclipse-business-media/contact-us/) - [Subscribe for free](https://www.sepscience.com/subscribe/) [![Separation Science](https://blog.sepscience.com/hubfs/Sepscience_Dec2016/images/-resized-strch-SepSci_WebHeader_v3.png)](https://www.sepscience.com/) - [Food](https://www.sepscience.com/food) - [Enviro](https://www.sepscience.com/enviro) - [Pharma](https://www.sepscience.com/pharma) - [Bio Clinical](https://www.sepscience.com/bioclinical) - [LC](https://www.sepscience.com/lc) - [GC](https://www.sepscience.com/gc) - [MS](https://www.sepscience.com/ms) - [Methods & Applications](https://www.sepscience.com/methods-and-applications/) - [Webinars & eSeminars](https://www.sepscience.com/webinars-and-eseminars/) - [Videos & Tutorials](https://www.sepscience.com/videos-and-tutorials/) - [Home](https://www.sepscience.com/) - [Get in Touch with Us](https://www.sepscience.com/) - [Home](https://www.sepscience.com/pharma) - Pharmaceutical Analysis[Pharmaceutical Analysis](https://blog.sepscience.com/pharmascience) - [Pharmaceutical Analysis Blog](https://blog.sepscience.com/pharmascience/topic/methods-applications) # Pharmaceutical Analysis ### [High Speed LC Analysis of Pharmaceutical Impurities in Compliance with European Pharmacopoeia](https://blog.sepscience.com/pharmascience/high-speed-lc-analysis-of-pharmaceutical-impurities-in-compliance-with-european-pharmacopoeia) Shimadzu has produced an application note describing a newly developed method for the high-speed analysis of pharmaceuticals and related substances in compliance with *European Pharmacopoeia* using the Nexera-i MT. [Read More](https://blog.sepscience.com/pharmascience/high-speed-lc-analysis-of-pharmaceutical-impurities-in-compliance-with-european-pharmacopoeia) ### [Monitoring VOC Emissions from Respiratory Medical Devices in Accordance with ISO 18562](https://blog.sepscience.com/pharmascience/monitoring-voc-emissions-from-respiratory-medical-devices-in-accordance-with-iso-18562) Markes International has produced an application note describing the monitoring of potentiallyharmful volatile and semi-volatile organic compounds (VOCs and SVOCs) emitted from respiratory medical devices, in accordance with the recently-released... [Read More](https://blog.sepscience.com/pharmascience/monitoring-voc-emissions-from-respiratory-medical-devices-in-accordance-with-iso-18562) ### [Transition to modernized pharmacopoeial methods using ion chromatography](https://blog.sepscience.com/pharmascience/transition-to-modernized-pharmacopoeial-methods-using-ion-chromatography) Many existing pharmaceutical and biopharmaceutical assays are time consuming, labor-intensive, involve hazardous chemicals, require extensive analyst training, and may yield significant measurement errors. [Read More](https://blog.sepscience.com/pharmascience/transition-to-modernized-pharmacopoeial-methods-using-ion-chromatography) ### [Current Methodologies for Drugs of Abuse Urine Testing](https://blog.sepscience.com/pharmascience/current-methodologies-for-drugs-of-abuse-urine-testing) Biotage has produced a white paper examining a number of aspects of sample preparation and their impact on the success of subsequent LC-MS/MS analysis of broad urine panels. [Read More](https://blog.sepscience.com/pharmascience/current-methodologies-for-drugs-of-abuse-urine-testing) ### [Chiral Multicolumn Method Development on the Agilent 1260 Infinity II Analytical SFC System](https://blog.sepscience.com/pharmascience/chiral-multicolumn-method-development-on-the-agilent-1260-infinity-ii-analytical-sfc-system) Agilent Technologies has produced an application note demonstrating the use of the Agilent ChemStation Method Scouting Wizard for the development of a chiral separation method on the Agilent 1260 Infinity II Analytical SFC system. The SFC system was... [Read More](https://blog.sepscience.com/pharmascience/chiral-multicolumn-method-development-on-the-agilent-1260-infinity-ii-analytical-sfc-system) ### [LC-MS/MS Bioanalysis of Trastuzumab Using Fab-Selective Proteolysis ‘nSMOL’](https://blog.sepscience.com/pharmascience/lc-ms/ms-bioanalysis-of-trastuzumab-using-fab-selective-proteolysis-nsmol) Shimadzu has produced an application note demonstrating how the LC-MS/MS bioanalysis of antibody drugs has been significantly simplified by this unique nSMOL technology. In this application, the analysis of Trastuzumab is discussed.  [Read More](https://blog.sepscience.com/pharmascience/lc-ms/ms-bioanalysis-of-trastuzumab-using-fab-selective-proteolysis-nsmol) ### [Analysis of Polysorbate 80 in IgG Aqueous Solution by Online SPE Using Shim-pack MAYI Column – Part 2](https://blog.sepscience.com/pharmascience/analysis-of-polysorbate-80-in-igg-aqueous-solution-by-online-spe-using-shim-pack-mayi-column-part2) Continued from the previous application (Part 1), Shimadzu has produced an application note demonstrationg how the same online-SPE system using Shim-pack MAYI-ODS was now deployed for the detection of various impurities contained in polysorbate 80... [Read More](https://blog.sepscience.com/pharmascience/analysis-of-polysorbate-80-in-igg-aqueous-solution-by-online-spe-using-shim-pack-mayi-column-part2) ### [Analysis of Polysorbate 80 in IgG Aqueous Solution by Online SPE Using Shim-pack MAYI Column – Part 1](https://blog.sepscience.com/pharmascience/analysis-of-polysorbate-80-in-igg-aqueous-solution-by-online-spe-using-shim-pack-mayi-column-part-1) Shimadzu has produced an application note demonstrating how the analysis of polysorbate 80 in IgG aqueous solution is simplified using an online-SPE system. [Read More](https://blog.sepscience.com/pharmascience/analysis-of-polysorbate-80-in-igg-aqueous-solution-by-online-spe-using-shim-pack-mayi-column-part-1) ### [Detection of Protein Aggregates using a Mass Spectrometric Approach](https://blog.sepscience.com/pharmascience/detection-of-protein-aggregates-using-a-mass-spectrometric-approach) Shimadzu has produced an application note describing the detection of protein aggregates using a mass spectrometric approach with versatile MALDI-TOF instrumentation. [Read More](https://blog.sepscience.com/pharmascience/detection-of-protein-aggregates-using-a-mass-spectrometric-approach) ### [Proof of Equivalency for the Analysis of Beta-Blockers](https://blog.sepscience.com/pharmascience/proof-of-equivalency-for-the-analysis-of-beta-blockers) Agilent Technologies has produced an application note that shows the seamless transfer of a method for the analysis of beta-blockers from an Agilent 1260 Infinity LC to an Agilent 1260 Infinity II LC. It proves that equivalent results in terms of... [Read More](https://blog.sepscience.com/pharmascience/proof-of-equivalency-for-the-analysis-of-beta-blockers) ### [High-Throughput LC/MS/MS Method for the Analysis of Pain Management Drugs](https://blog.sepscience.com/pharmascience/high-throughput-lc/ms/ms-method-for-the-analysis-of-pain-management-drugs) PerkinElmer has produced an effective LC/MS/MS method providing a fast, accurate and reproducible solution for the analysis of pain management drugs. [Read More](https://blog.sepscience.com/pharmascience/high-throughput-lc/ms/ms-method-for-the-analysis-of-pain-management-drugs) ### [Proof of Equivalency for the Analysis of Local Anesthetics](https://blog.sepscience.com/pharmascience/proof-of-equivalency-for-the-analysis-of-local-anesthetics) Agilent Technologies has produced an application note proving equivalency of the Agilent 1200 Series Binary LC and the Agilent 1260 Infinity II LC for the analysis of local anesthetics. [Read More](https://blog.sepscience.com/pharmascience/proof-of-equivalency-for-the-analysis-of-local-anesthetics) ### [LC Analysis of Vitamin D Epimers on Raptor FluoroPhenyl Columns](https://blog.sepscience.com/pharmascience/lc-analysis-of-vitamin-d-epimers-on-raptor-fluorophenyl-columns) Restek has produced an application note demonstrating how the Raptor FluoroPhenyl column is a good choice for vitamin D analysis as opposed to C18 columns. [Read More](https://blog.sepscience.com/pharmascience/lc-analysis-of-vitamin-d-epimers-on-raptor-fluorophenyl-columns) ### [How to Develop Successful LC-MS/MS Pain Medication Screening Methodologies](https://blog.sepscience.com/pharmascience/effective-therapeutic-drug-monitoring-by-lc-ms/ms) Restek has produced an application note demonstrating how its Raptor™ Biphenyl column is ideal for developing successful LC-MS/MS pain medication screening methodologies. As a result big pain assays no longer become a big pain. [Read More](https://blog.sepscience.com/pharmascience/effective-therapeutic-drug-monitoring-by-lc-ms/ms) ### [Profiling the Distribution of N-Glycosylation in Therapeutic Antibodies](https://blog.sepscience.com/pharmascience/profiling-the-distribution-of-n-glycosylation-in-therapeutic-antibodies) SCIEX has produced an application note demonstrating how a comprehensive MS/MS analysis of glycopeptides can be achieved by targeting the known nature of the glycosylation structures using the QTRAP® 6500 system.  [Read More](https://blog.sepscience.com/pharmascience/profiling-the-distribution-of-n-glycosylation-in-therapeutic-antibodies) [Previous](https://blog.sepscience.com/pharmascience/topic/methods-applications/page/3) [Next](https://blog.sepscience.com/pharmascience/topic/methods-applications/page/5) ### Posts by Topic - [Methods & Applications (63)](https://blog.sepscience.com/pharmascience/topic/methods-applications) - [Biopharma (54)](https://blog.sepscience.com/pharmascience/topic/biopharma) - 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