Pharma Science

Analysis of Polysorbate 80 in IgG Aqueous Solution by Online SPE Using Shim-pack MAYI Column – Part 2

Continued from the previous application (Part 1), Shimadzu has produced an application note demonstrationg how the same online-SPE system using Shim-pack MAYI-ODS was now deployed for the detection of various impurities contained in polysorbate...

Analysis of Polysorbate 80 in IgG Aqueous Solution by Online SPE Using Shim-pack MAYI Column – Part 1

Shimadzu has produced an application note demonstrating how the analysis of polysorbate 80 in IgG aqueous solution is simplified using an online-SPE system.

Detection of Protein Aggregates using a Mass Spectrometric Approach

Shimadzu has produced an application note describing the detection of protein aggregates using a mass spectrometric approach with versatile MALDI-TOF instrumentation.

Proof of Equivalency for the Analysis of Beta-Blockers

Agilent Technologies has produced an application note that shows the seamless transfer of a method for the analysis of beta-blockers from an Agilent 1260 Infinity LC to an Agilent 1260 Infinity II LC. It proves that equivalent results in terms of...

High-Throughput LC/MS/MS Method for the Analysis of Pain Management Drugs

PerkinElmer has produced an effective LC/MS/MS method providing a fast, accurate and reproducible solution for the analysis of pain management drugs.

Proof of Equivalency for the Analysis of Local Anesthetics

Agilent Technologies has produced an application note proving equivalency of the Agilent 1200 Series Binary LC and the Agilent 1260 Infinity II LC for the analysis of local anesthetics.

LC Analysis of Vitamin D Epimers on Raptor FluoroPhenyl Columns

Restek has produced an application note demonstrating how the Raptor FluoroPhenyl column is a good choice for vitamin D analysis as opposed to C18 columns.

How to Develop Successful LC-MS/MS Pain Medication Screening Methodologies

Restek has produced an application note demonstrating how its Raptor™ Biphenyl column is ideal for developing successful LC-MS/MS pain medication screening methodologies. As a result big pain assays no longer become a big pain.

Profiling the Distribution of N-Glycosylation in Therapeutic Antibodies

SCIEX has produced an application note demonstrating how a comprehensive MS/MS analysis of glycopeptides can be achieved by targeting the known nature of the glycosylation structures using the QTRAP® 6500 system. 

Cleaning Validation for Pharmaceutical Manufacturing by Online SFE-SFC

Shimadzu has produced a paper that evaluates the application of a novel on-line supercritical fluid extraction/chromatography system for cleaning validation in pharmaceutical manufacturing.The benefits of online SFE/SFC are shown to be data...

Separation of Statistic MMA-MAA Copolymers using Gradient SEC

PSS has produced an application note describing how gradient SEC is the method of choice for characterizing statistic copolymers of methyl methacrylate (MMA) and methacrylic acid (MAA) that are widely used in pharmaceutical applications. 

Method Equivalency for The Analysis of Paracetamol

Agilent Technologies has produced an application note describing a method to achieve seamless method transfer for the analysis of paracetamol and its impurities and signficantly decrease analysis time.

    

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