Pharmaceutical Analysis

In previous articles HPTLC (High Performance Thin-Layer Chromatography) applications for a series of medicinal plants, such as Ginkgo, Hypericum or Ginseng, have been presented.

In convergence chromatography (CC), the modes of interaction between the stationary phase and the solute are numerous, including hydrogen bonding, hydrophobic interactions, dipolar and polarizability interactions and solute partitioning [1]. These...

Looking for new and improved technologies to advance your peptide mapping strategies? Do you want to overcome automation problems with your therapeutic protein workflows? If so, signup for this educational presentation...

SUCCESSFUL CHROMATOGRAPHY STARTS AT THE BEGINNING

Understanding the basics of any chromatographic technique is the first step towards achieving your analytical goals and allowing correct decision making and effective pharmaceutical method...

Are you involved in biopharmaceutical research? Would you like to find out more about the role of light scattering and associated techniques in characterizing biological molecules? This presentation from Separation Science, in collaboration with...

Thermo Fisher Scientific has produced an application note with the goal of evaluating the performance of a new Thermo Scientific™ TriPlus™ 500 Gas Chromatography Headspace Autosampler for the determination of residual solvent content in...

Want to read a great introduction to SEC for protein analysis, and the advantages of new-generation agarose columns - then take a look at this new white paper from GE Healthcare.

Do you currently experience a lack of reliable methods for the quantification of submicron (0.1 to 1 mm) protein aggregates? Would you like to learn more about how field-flow fractionation and light scattering are suitable techniques for studying...

Do you encounter challenges with polymer characterization and would like to learn more about cutting-edge technology that can help identify and overcome any shortfalls of your current techniques? If so, this presentation from Separation Science, in...

Biopharmaceuticals represent protein molecules produced by genetically engineered living cells using large scale industrial bioprocessing. The complexity of these molecules requires advanced analytical characterisation strategies to ensure that...

This application note describes a method for the preparative purification of Ibuprofen and its analogs using the Prominence™ UFPLC designed to improve the efficiency of your workflow.

In this study, a successful micro LC-MS/MS method for the highly sensitive quantitation of desmopressin in human plasma is demonstrated. It shows how the QTRAP^® 6500+ LC MS/MS system with OptiFlow™ Source coupled with a M5 MicroLC system provides...

This application note demonstrates a method for the high-speed analysis of pramipexole following the draft guidance of International Harmonization of Pharmacopoeias. It uses Shimadzu's integrated LC system, the Nexera™ - i MT. 

This study describes in detail an improved immunoaffinity-micro LC-MS/MS workflow for quantifying trastuzumab emtansine in mouse plasma using the SCIEX 6500+ QTRAP^®System with OptiFlow™ Turbo V source and M5 MicroLC System.

This application demonstrates an effective method for the analysis irbesartan using Shimadzu's integrated LC system, the Nexera™ - i MT.