Pharmaceutical Analysis

Separation Science, in collaboration with Agilent, offers an eBook containing a selection of application notes relevant for pharmaceutical and clinical analysis using gas chromatography (GC). Discover an effective method for the analysis of USP<467>...

Analysis of nitrosamines in pharmaceutical products presents certain unique challenges in terms of interferences, elevated baselines, inconsistencies in quantifications and decreasing method performance. Most of these challenges can be addressed by...

Separation Science met with Agilent experts to discuss root causes for the presence of nitrosamines in drug substances and drug products, the current regulatory guidance to help identify these mutagenic impurities, the key analytical strategies that...

Separation Science, in collaboration with Agilent, offers an eBook covering new and advanced methods, applications and case studies in automated sample preparation workflows.

Separation Science, in collaboration with Agilent, offers a technology guide that provides key information for individuals looking to improve knowledge and analytical skills in the trace analysis of nitrosamines in pharmaceutical products. From...

Charge variant analysis is a demanding application for applied liquid chromatography systems due to the use of highly corrosive buffer salts in combination with very shallow gradients for optimal separation. Separation Science, in collaboration with...

With challenging applications and strict time and quality constraints, biopharmaceutical analysis can be especially demanding.

Separation Science, in collaboration with Agilent, offers an eBook covering advanced methods for the analysis of biomolecules, including monoclonal antibodies and biotherapeutics. Glycan and glycosylation analysis, charge variant analysis and...

Involved in CQA monitoring? Looking for reliable HPLC methods suitable for the various aspects of this work? If so, the 'Critical Quality Attributes: Applications Compendium' is what you're looking for.

This application from Agilent describes the 2D-LC analysis of complex peptones. Active solvent modulation proved to be valuable to maintain chromatographic performance and avoid breakthrough in the second dimension.

Phosphorylated compounds such as nucleotides are known to interact with stainless steel components leading to recovery issues in HPLC and LC/MS. Instrument and column inertness ensure successful analysis. Discover more about the bio-inert analysis...

Would you like to learn more about the vital role of compendial methods in pharmaceutical analysis and how, by making adjustments to them, laboratory efficiency can be increased and cost decreased? If so, this on-demand webinar will provide the...

Peptide mapping is critical for characterizing protein drugs and monitoring product critical quality attributes (CQAs) in biopharma. Due to the heterogenous nature of protein drugs, comprehensive analytical characterization is required for getting...

Agilent Technologies has produced an application note describing the separation and purification of acetaminophen (paracetamol) and six common impurities listed in the European and United States Pharmacopoeias.

Agilent Technologies has produced an application note describing the quantitative determination of the drug diclofenac and its related compounds in human plasma. Compounds were quantified based on measurement of the Cl heteroatom using...