Pharmaceutical Analysis

Agilent Technologies has produced an application note demonstrating the separation of enantiomers of amphetamines and their positional isomers on chiral phase columns using SFC with mass spectrometry.

Agilent Technologies has produced an application note presenting a novel tool to study E&L compounds using a high-resolution accurate mass GC/Q-TOF equipped with a low-energy EI capable ion source.

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Agilent Technologies has produced an application note demonstrating the use of high-resolution (HiRes) sampling 2D-LC for the separation and detection of impurities, exemplified for different isomers of chlorodifluorobenzoic acid at relative...

Agilent Technologies has produced an application note demonstrating the use of the Agilent ChemStation Method Scouting Wizard for the development of a chiral separation method on the Agilent 1260 Infinity II Analytical SFC system. The SFC system was...

Extractables and leachables (E&Ls) are small molecules present in a polymer system including antioxidants, surfactants, slip agents, plasticizers, acid scavengers, cross linking agents, residual monomers and oligomers, polymerization side products...

Recombinant biopharmaceutical proteins are expressed in host cell systems that contain numerous host cell proteins (HCPs). Even after a series of purifications, low levels of HCPs can remain in the purified biotherapeutics, which could reduce drug...

Peptide mapping is vital to understanding the structure of proteins and monitoring critical quality attributes. To create effective, high-quality biotherapeutics, you have to get this right. Renowned for accuracy and reliability, Agilent offers a...

The presentation summarizes the latest updates for the analysis of biopharmaceuticals using the Agilent 1290 Infinity II 2D-LC Solution. After a short introduction to the principle mode of operation, I will explain the latest 2D-LC modes; multiple...

Routine analysis of therapeutic protein N-glycosylation has become important in biopharma discovery, development and QC labs. This presentation will briefly review recent advances in automated sample preparation and ultra-high performance HILIC...

Biotherapeutics – recombinant proteins, such as monoclonal antibodies – are highly complex molecules produced by fermentation. Unlike small molecule drugs they can contain numerous sites of heterogeneity as well as other impurities (which can arise...

Want to know more about new methods for biotherapeutics analysis? Looking to streamline your bioprocess workflows? Need help with your data quality? If so, then this on-demand event is for you...

Agilent Technologies has produced an application note that shows the seamless transfer of a method for the analysis of beta-blockers from an Agilent 1260 Infinity LC to an Agilent 1260 Infinity II LC. It proves that equivalent results in terms of...

Agilent Technologies has produced an application note proving equivalency of the Agilent 1200 Series Binary LC and the Agilent 1260 Infinity II LC for the analysis of local anesthetics.

Agilent Technologies has produced an application note describing a method to achieve seamless method transfer for the analysis of paracetamol and its impurities and signficantly decrease analysis time.