Pharmaceutical Analysis

Many existing pharmaceutical and biopharmaceutical assays are time consuming, labor-intensive, involve hazardous chemicals, require extensive analyst training, and may yield significant measurement errors.

Biotage has produced a white paper examining a number of aspects of sample preparation and their impact on the success of subsequent LC-MS/MS analysis of broad urine panels.

Agilent Technologies has produced an application note demonstrating the use of the Agilent ChemStation Method Scouting Wizard for the development of a chiral separation method on the Agilent 1260 Infinity II Analytical SFC system. The SFC system was...

Extractables and leachables (E&Ls) are small molecules present in a polymer system including antioxidants, surfactants, slip agents, plasticizers, acid scavengers, cross linking agents, residual monomers and oligomers, polymerization side products...

Recombinant biopharmaceutical proteins are expressed in host cell systems that contain numerous host cell proteins (HCPs). Even after a series of purifications, low levels of HCPs can remain in the purified biotherapeutics, which could reduce drug...

Peptide mapping is vital to understanding the structure of proteins and monitoring critical quality attributes. To create effective, high-quality biotherapeutics, you have to get this right. Renowned for accuracy and reliability, Agilent offers a...

The presentation summarizes the latest updates for the analysis of biopharmaceuticals using the Agilent 1290 Infinity II 2D-LC Solution. After a short introduction to the principle mode of operation, I will explain the latest 2D-LC modes; multiple...

Routine analysis of therapeutic protein N-glycosylation has become important in biopharma discovery, development and QC labs. This presentation will briefly review recent advances in automated sample preparation and ultra-high performance HILIC...

Biotherapeutics – recombinant proteins, such as monoclonal antibodies – are highly complex molecules produced by fermentation. Unlike small molecule drugs they can contain numerous sites of heterogeneity as well as other impurities (which can arise...

Want to know more about new methods for biotherapeutics analysis? Looking to streamline your bioprocess workflows? Need help with your data quality? If so, then this on-demand event is for you...

Polymeric and other content can contribute up to 90% of the total mass in a pharmaceutical product, where excipients play a critical role in the drug’s performance. In just one example of the importance of excipient properties for therapeutic...

Shimadzu has produced an application note demonstrating how the LC-MS/MS bioanalysis of antibody drugs has been significantly simplified by this unique nSMOL technology. In this application, the analysis of Trastuzumab is discussed. 

Continued from the previous application (Part 1), Shimadzu has produced an application note demonstrationg how the same online-SPE system using Shim-pack MAYI-ODS was now deployed for the detection of various impurities contained in polysorbate 80...

Shimadzu has produced an application note demonstrating how the analysis of polysorbate 80 in IgG aqueous solution is simplified using an online-SPE system.

Looking to improve the yield and purity of your target proteins? Then don't miss this on-demand presentation...