Join us for this on-demand presentation and discover a method that can be used for performing structurally-resolved mass isotopologue distribution analysis of metabolites.
Separation Science in collaboration with SCIEX

Recent Posts
This on-demand webinar presents a case study of risk assessment implementation and covers analytical methodologies for N-nitrosamines with their challenges and suggested solutions. By watching this presentation you will: 1) Get background...
The therapeutic potential of biologic modalities has increased, driving an inevitable move toward exploring more complex biotherapeutic molecule classes. As biotherapeutics become more complex, there is still a demand for superior quantification...
In this study, a successful micro LC-MS/MS method for the highly sensitive quantitation of desmopressin in human plasma is demonstrated. It shows how the QTRAP® 6500+ LC MS/MS system with OptiFlow™ Source coupled with a M5 MicroLC system provides...
This study describes in detail an improved immunoaffinity-micro LC-MS/MS workflow for quantifying trastuzumab emtansine in mouse plasma using the SCIEX 6500+ QTRAP®System with OptiFlow™ Turbo V source and M5 MicroLC System.
SCiEX has produced a technical note describing an immunoaffinity-high resolution accurate mass assay for the pre-clinical quantification of Trastuzumab in rat plasma.
Find, Identify and Confirm Peptide Catabolites Using MetabolitePilotTM 2.0 Software and the Advanced Biotransform Solution.
SCIEX has produced a technical note describing metabolite identification of payload species of antibody drug conjugates with noncleavable linkers using MetabolitePilot™ 2.0 software and TripleTOF® 6600 systems.
This technical note from SCIEX will highlight how to implement a complete and easy-to-use Multiple Attribute Methodology (MAM) workflow for biotherapeutic PQA monitoring using accurate mass LC–MS. It will demonstrate how this new streamlined MAM...
Rapid development of sensitive and selective peptide bioanalytical methods are required to support the expanding protein component of pharmaceutical companies’ drug pipeline. Choosing the best MRM for a large molecule peptide or protein is a...
SCIEX introduces its OptiFlow Quant Solution providing microflow sensitivity and analytical flow usability. Learn how to enhance your sensitivity for challenging analytes such as peptides, mAbs and ADCs.
Attend this on-demand webinar and learn about workflows involved in pharmaceutical impurity analysis and API stability studies, and how to deliver confidence in the identification of unknown impurities...
SCIEX has produced an application note demonstrating how to monitor biotherapeutic oxidation levels in a simple and automated way using the X500B QTOF system and powerful BioPharmaView™ Software.
SCIEX has produced an application note demonstrating using a reproducible and robust method for analysing intact biotherapeutic proteins on the X500B QTOF System with automated batch processing using BioPharmaView™ software.
SCIEX has produced an application note describing a simple and rapid methodology to characterize and quantify differences between biotherapeutic batches, using high-resolution peptide mapping by LC-MS.
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