Liquid Chromatography

SEC overview of the principles and techniques to obtain reliable protein size-based-separations

Size-Exclusion Chromatography (SEC) is a powerful technique for protein characterization that requires an understanding of the principles to be successful. In this open-access course, we will discuss the history and science of SEC, its strengths and...

What’s New at the Largest Conference in the World Covering All Aspects of Separations and Analyses Carried Out in Liquid-Phase

Join scientists from around the world at the 50th sequel of the longest-running, largest, and most recognized conference in the world covering all aspects of Separations and Analyses carried out in Liquid Phase. HPLC 2022 will take place on June...

PolyAnalysis Forum - New Polymers with Complex Architectures:  Why and how?

Register now for the PolyAnalysis Forum!

Sample Preparation in GPC/SEC

Want to get a better understanding of the various sample preparation procedures available for GPC/SEC analysis, and what to consider when selecting one? If so, this tutorial is for you...

What's New at the Largest Liquid-Phase Separations Conference in the World

Mark your calendar to attend HPLC 2020 on June 20-25, 2020 in beautiful San Diego, CA, USA along the dramatic Pacific coastline. The HPLC conference will celebrate its 50th edition in 2020, and has grown to become the largest and most visible...

Studying aggregation and degradation over time with SEC

Do you suffer from protein aggregation, oligomerization or degradation? If so, analytical SEC is a great diagnostic tool... 

Comparing silica and agarose resins for analysis of proteins with SEC

Silica- and agarose-based resins are the two most used types of size exclusion chromatography (SEC) resins available for protein analysis purposes. But how do they compare and which should you use?

Shodex size-exclusion chromatography tutorial

This video provides a general overview of size-exclusion chromatography.Size-exclusion chromatography is used for analysing high molar mass compounds, such as synthetic polymers, bio-polymers, like proteins and antibodies, polysaccharides and other...

Understanding the benefits of new generation agarose-based SEC resins for biomolecules

Looking for a solution to biomolecule analysis? Familiar with size exclusion chromatography but need improved analysis? If so, this article outlining new generation agarose-based resins might just be what you need...

Leading the Way to Ensure the Separation Sciences Remain a Powerful Analytical Tool

Mark your calendar to attend HPLC 2018 on July 29-August 2, 2018 in Washington, DC USA. The HPLC conference will celebrate its 47th anniversary in 2018, and has grown to become the largest and most visible international conference series dedicated...

Protein analysis with size exclusion chromatography

Looking to improve your protein analysis skills? Interested in how size exclusion chromatography can give you an analytical advantage in this field?

GPC/SEC Analysis of Polymer Branching

Malvern has produced an application note describing the GPC (or equivalently SEC) analysis of branching in polyvinylpyrrolidone (PVP).

Understanding GPC/SEC - Finding the Right Particle Size and Pore Size

Want to understand what the correct criteria for column selection should be based on? If so, this tutorial is for you...

Understanding GPC/SEC - Unexpected Peak Shapes

Do you find weird peak shapes in your chromatograms? Not sure if they are real or artifacts?

Understanding GPC/SEC - How to deal with pressure problems

So you're using gel permeation chromatography (GPC) / size exclusion chromatography (SEC) but are experiencing problems with your system pressure. What do you do?

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