Liquid Chromatography

Having trouble separating compounds, and wondering what is the single most important parameter to change? Questions over characterizing high molecular weight compounds such as oligonucleotides? Tackle column selection like an expert by registering...

Watch this on-demand webinar to learn about the key considerations when selecting a LIMS to best meet your goals and elevate your lab.

Separation Science, in collaboration with Waters, has developed a series of open-access online LC learning courses covering choosing base particles, ligands and hardware for robust chromatographic separations. We are pleased to offer a new full...

Karl Fischer titration is still the most used, most accurate, and fastest method to determine water content in all kinds of sample matrices.

LC-MS systems are complex and sensitive instruments, and even minor issues can lead to inaccurate results or instrument downtime, resulting in financial losses and delayed research.

Drinking Water Total Oxidized Nitrogen for the Thermo Scientific Gallery Discrete Analyzer offers laboratories a fully automated approach to compliant nitrate and nitrite testing that minimizes the challenges associated with traditional cadmium...

The Thermo Scientific discrete analyzer method offers laboratories an automated, high-throughput option for regulated testing for orthophosphate in drinking water. Walk-away automation simplifies drinking water analyses and reduces errors. 

This article from Issue 14 of the Analytix Reporter discusses theHPTLC system suitability test (SST) which often qualifies only a limited region of the chromatogram. The newly developed Universal HPTLC Mix (UHM) enables TLC users to efficiently and...

This article from Issue 14 of the Analytix Reporter discusses thin-layer chromatography (TLC), a fast, easy-to-use, cost-efficient, and highly versatile separation technique for qualitative and quantitative analysis. It describes some of the key...

View our on-demand webinar to learn about LIMS, delivering knowledge from data, automation solutions, and intuitive workflows.

Are you new to HPLC, or do you supervise new users of HPLC? 'Fundamentals of HPLC' is taught by Tom Jupille, a world-class expert in HPLC, and represents an opportunity to give new users a firm grounding in the fundamentals of HPLC economically and...

A comprehensive course in the systematic development of liquid chromatography separations using QbD principles. Here we review some basic chromatographic measurements – N, α, k, As, TF, Rs – and how these play into a method development strategy...

A comprehensive course in the systematic development of liquid chromatography separations using QbD principles. We examine the processes that influence band spreading and how columns have evolved to their present configuration. The choice of the...

A comprehensive course in the systematic development of liquid chromatography separations using QbD principles. We concentrate on reversed-phase separations in this course, because the majority of HPLC and UHPLC methods use this technique. How does...

A comprehensive course in the systematic development of liquid chromatography separations using QbD principles. How can we take advantage of pH to improve the separation and what are the pitfalls when we do use pH for this purpose? Why is...