Liquid Chromatography Blog

Perform Analysis of Choline and Acetylcholine in Rat Cerebrospinal Fluid Samples by SFC

Shimadzu has produced an application note describing the SFC analysis of choline in a rat cerebrospinal fluid sample by direct injection of the cerebrospinal fluid to the Nexera-UC system.

Application of Online SFE-SFC-PDA for Cleaning Validation

Shimadzu has produced an application note describing the Nexera-UC online SFE-SFC system that was used for efficient analysis of alkylbenzenesulfone from a swab (cloth used for surface wiping to show safety at a pharmaceutical manufacturing site).

High-Precision Temperature Control for SFC Using the Agilent 1260 Infinity II Multicolumn Thermostat

Agilent Technologies has produced a Technical Overview demonstrating the use of the Agilent 1260 Infinity II Multicolumn Thermostat in the Agilent InfinityLab Supercritical Fluid Chromatography (SFC) Solution. It describes how the post column...

How to Achieve High Temperature GPC Analysis of Polyphenylene Sulfide

Tosoh Bioscience has produced an application note describing how polyphenylene sulfide (PPS) analysis can be successfully achieved using its EcoSEC high temperature GPC system.

Effective Analysis of Asphalt Binders

Tosoh Bioscience has produced an application note describing the analysis of asphalt binders using gel permeation chromatography.

Analysis of Bio-Inspired Alkylalanoid Polymers

Tosoh Bioscience has produced an application describing how to improve reproducibility of MW measurements of polypeptoids using an EcoSEC GPC system.

Monitoring Single-Chain Nanoparticle Formation

Tosoh Bioscience has produced an application note describing how to monitor single-chain nanoparticle formation and characterize nanoparticles using multi-pore TSKgel GPC columns.

High Temperature GPC Analysis of a Polypropylene Copolymer

Tosoh Bioscience has produced an application note determining the molar mass averages and polydispersity of two polypropylene random copolymer samples via refractive index (RI) detection using the EcoSEC High Temperature GPC System and TSKgel...

Trends and Applications in GPC Polymer Analysis

Gel permeation chromatography (GPC) is a valuable and well established tool for the chemical industry when it comes to the determination of the molecular weight and the molecular weight distribution of polymers.

Analysis of Polymers for Therapeutics

Tosoh Bioscience has produced an application note demonstrating how GPC was applied to analyse and differentiate the molar mass averages and distributions of four block copolymers intended to be used in a polymer-based therapeutic.

Supercritical Fluid Chromatography with Flexible Injection Volumes at Highest Precision

Agilent Technologies has produced a Technical Overview demonstrating the injection principle used in the Agilent 1260 Infinity II SFC Multisampler. In this instrument, the sample volume is drawn under atmospheric pressure conditions, pressurized...

Universal Analytical Method Development for Various HPLC Systems

Agilent Technologies has produced an application note describing a combined approach to analytical method development and method transfer by direct emulation of different target HPLC systems. The proposed workflow presents a general approach to...

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