Gas Chromatography

Continuing our discussion of the three configurations of capillary column backflush, we cover the coated pre-column configuration.

We continue the previous article's backflush discussion with a description of the most common form of backflush: post-column backflush.

In this technical article we introduce the concepts of backflushing capillary columns.

Continuing the previous discussion of the most popular GC detector, the FID, we cover deviations from typical unit carbon response, optimization and troubleshooting.

In this technical article we initiate a discussion on the workhorse detector of gas chromatography: the flame ionization detector.

In Part 3 we bring together the retention mechanism concepts discussed earlier to form a simple view of the nature of selectivity in liquid stationary phases used in gas chromatography.

To fully grasp the concepts of retention and selectivity of GC stationary phases, one must first understand the fundamental intermolecular interactions that lead to retention. In the second part of this series we discuss polar interactions; the...

To fully grasp the concepts of retention and selectivity of GC stationary phases, one must first understand the fundamental intermolecular interactions that lead to retention. This article discusses the most dominant of those interactions –...

Here, we tackle another potential problem of hot split injection: sample decomposition. Decomposition changes the nature of components in the original sample, affecting the “recovery” of target compounds. This in turn introduces errors in analytical...

This technical article discusses the process of hot split injections and the sources of discrimination, which are one of the potential downsides of this technique.

This article will discuss split injections with a hot split/splitless inlet. This is the most popular inlet and sampling mode for capillary GC. The focus will be on the basic concepts and flow paths. Later articles will cover liner choice,...

This technical article provides a general overview of the purpose of GC columns, key processes involved and a description of differences between them.

This video will show you how to adjust your run conditions when switching to a column with smaller dimensions for the purposes of reducing your run time. It explains how the combination of using a GC Accelerator oven insert kit and adapting an...

Learn more about detectors for GC and when to use them...

This technical article covers the general function of GC inlets and describes some common attributes and differences whilst providing a context for future articles covering inlets in more detail.