Mass Spectrometry

The Asia-Oceania Mass Spectrometry Conference (AOMSC), held from 5th-7th January 2020, Macau, is a conference collaboratively organized by the Mass Spectrometry societies in the Asia/Oceania region. The overall theme of the conference is “The Art...

Plasma Spectrochemistry for Trace Element, Stable Isotope, Elemental Imaging and Speciation Analyses.

The 2020 Winter Conference on Plasma Spectrochemistry, 21st in a series of biennial meetings, features developments in plasma spectrochemical...

This technical article describes how two new techniques have arisen which result in more complete fragmentation with better predictability for multiple-charge precursor ions. The techniques are electron capture dissociation (ECD) and electron...

We typically think of a mass spectrum as consisting of a precursor ion at high m/z and a series of increasingly lower m/z product (fragment) ions. These types of mass spectra are shown in training courses and textbooks as didactic examples because...

In this technical article the use of multiple-charge ions in protein and peptide analysis, such as the determination of intact protein molecular mass is discussed.

Structural Identification of Unknowns from Spectra Obtained Using LC/MS and CAD Techniques and EI Mass Spectral Database.

This installment in the series on NIST 11 (National Institute of Standards and Technology) is about the Incremental Name Search , replicate spectra, and the NIST GC Methods, and Retention Index Database.

The previous two installments provided information on the NIST (National Institute of Standards and Technology)/EPA/NIH Mass Spectral Database, past and present, and on the use of the NIST MS Search Program in identifying a compound from its mass...

NIST 11 (EPA/EPA/NIH Mass Spectral Database of Electron Ionization Data, GC Method/Retention Index Databases, A Database of Spectra Obtained Using MS/MS Techniques, v.2.0g of the NIST MS Search Program, MS Interpreter v.2, and AMDIS) What’s New and...

The NIST 11 (National Institute of Standards and Technology) Mass Spectral Database, the successor to the NIST 08, is a fully evaluated collection of electron ionization (EI) Mass Spectra, which also includes a growing number of MS/MS Spectra and GC...

In the previous MS Solutions we discussed MS/MS fragmentation of polypeptides, the types of ions formed, and the mechanism of their formation. In this part we will examine a tandem mass spectrum of a simple polypeptide and step through an...

This technical article explains the confusion resulting from molecular weight and the nominal mass, monoisotopic mass and average molar mass.

An illustrative example of the use of isotope peak ratios to determine an elemental composition.

This technical article comprises a discussion of the role of isotope peak intensities obtained using mass spectrometry in determining an elemental composition.

Mass spectrometry has long been a valuable quantitative tool used across many industries for numerous applications including food [1], beverage [2], pharma [3] and environmental analysis [4]. Its utility ranges from use as an alternative detector to...