Gas Chromatography

Learn about deconvolution, use of H2 as a carrier gas and tandem mass spectrometers

To develop a more in-depth understanding of gas chromatography-mass spectrometry. Deconvolution, use of H2 as a carrier gas, and tandem mass spectrometers are covered as special topics. Learn more about the mechanisms and benefits of deconvolution...

Framework for GC-MS Quantitative Analysis

To develop a more in-depth understanding of gas chromatography-mass spectrometry. The framework for GC-MS quantitation is explained. Topics and examples include integration parameters, linear and non-linear calibrations, calibration table choices,...

GC-MS Data Acquisition Parameters Explained

To develop a more in-depth understanding of gas chromatography-mass spectrometry. The differences between scan and selected ion monitoring are explained. The principles of proper selection of data acquisition parameters are covered in detail.

GC-MS Common Detectors

To develop a more in-depth understanding of gas chromatography-mass spectrometry, this course module describes common GC-MS detectors.

EI tuning concepts and how to spot detector failure

To develop a more in-depth understanding of gas chromatography-mass spectrometry. The various detectors used in mass spectrometry are described. Design features that reduce background noise are presented as well as are the general concept of...

A lab-wide approach for training your entire team

A successful lab requires more than just optmized workflows - at its heart it needs a confident, well-trained team of scientists.

Using the Chromatographic Modeler to Cut GC Method Development Time

Chromatographic laboratories face continual pressure to increase productivity while decreasing costs. With recent advances in available technology, additional flexibility in updated methods, and optimization of key instrument parameters, we can find...

Introducing a GC method development online tool

Chromatographic laboratories face continual pressure to increase productivity while decreasing costs. With recent advances in available technology, additional flexibility in updated methods, and optimization of key instrument parameters, we can find...

[Tutorial] Learn How to Reduce GC Method Development Time

Chromatographic laboratories face continual pressure to increase productivity while decreasing costs. With recent advances in available technology, additional flexibility in updated methods, and optimization of key instrument parameters, we can find...

Inlet Liners – Part 3

In this article we continue our liner discussion with a focus on liner volume. One of the most important liner design variables is the internal volume. Larger internal volumes are preferred for general use because they minimize the chance of vapor...

Inlet Liners – Part 2

Here we continue the discussion of inlet liners with a focus on liner outer diameter. It is important to realize that correct liner choice is most critical for:

Inlet Liners – Part 1

Selecting an appropriate inlet liner from the myriad available liner choices is a daunting task, especially when there is little qualified technical information about what differentiates them in terms of actual performance. Here we start discussing...

Activity and Decomposition

Although gas chromatography has many positive attributes as an analytical tool, its incompatibility with labile and active compounds is certainly one of its biggest weaknesses. Here we discuss evidence of sample decomposition and what we might do to...

Split Sample Introduction – Part 2: Measuring Flows, Liner Choice

Continuing our saga of split sample introduction, here we discuss measuring gas flows and liner selection for split injections.

Split Sample Introduction – Part 1: Background and Split Ratio

This technical article introduces the split sample concept and things to take note of for the best analytical results possible.

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