To develop a more in-depth understanding of gas chromatography-mass spectrometry. The various detectors used in mass spectrometry are described. Design features that reduce background noise are presented as well as are the general concept of electron multiplication and how to spot imminent detector failure before it is too late.

You should take this course if you are a user of gas chromatographs who is looking to further develop their method development and troubleshooting skills in GC-MS. A key demographic are companies that provide their employees with the yearly skill set development objectives. Even though supported by management, fulfilment of these objectives is difficult to accomplish through traditional training due to scheduling issues and frequent work-related interruptions. The online tutorial approach provides a unique solution by being accessible from anywhere with internet access, and at any time.

ats-STRIP

This course covers:

The various detectors used in mass spectrometry are described. Design features that reduce background noise are presented as well as are the general concept of electron multiplication and how to spot imminent detector failure before it is too late.

The relevant aspects of tuning a quadrupole MS for GC data acquisition are covered. An explanation of different types of tunes is provided. Example parameters and setpoints are explained as well as their effects on results. Development and use of custom tunes to meet method-specific requirements are presented as are concepts of dynamic ramping of source parameters. How to use historical tune results to track system performance changes is also explained.

This module has a complementary quiz. By correctly answering the quiz questions for all of the modules as part of the course you will be able to download your certificate of completion. Types of questions to expect are:

  • How do we calculate the peak width with linear quadrupole filters?
  • What is electron energy?
  • What indicates the source contamination?
  • Why do we need to compare tune files over time?
  • What is the use for different tunes?

 

Analytical Training Solutions, brought to you by Separation Science, is the leading global portal for fundamentals, best practice, troubleshooting and method development training for chromatographic and mass spectrometric techniques. Comprehensive, self-paced online courses and validated learning provides a unique education resource for analytical chemists. Currently, we offer HPLC training, LC-MS training, GC training and GC-MS training.

 

Published  Mar 27, 2023

Home 9 Techniques 9 Gas Chromatography 9 EI tuning concepts and how to spot detector failure