In forensic analysis, Solid Phase Extraction (SPE) allows analysts to selectively isolate and concentrate compounds, such as drug molecules, from complex matrices including blood, plasma, urine, and tissue. While SPE is a valuable sample preparation...
Separation Science in collaboration with UCT

Recent Posts
Separation Science, in collaboration with UCT, brings you the Forensic Sample Analysis eBook covering a range of solid-phase extraction (SPE) techniques and corresponding LC-MS/MS parameters for analysing various compounds in biological samples.
This on-demand webinar outlines methods for extracting a large drugs of abuse panel from urine and plasma using reverse-phase and mixed-mode sorbent chemistries. For further details and to register, click below.
This application note exploits the highly retentive, universal nature of UCT’s polymeric Styre Screen® HLD sorbent for the analysis of acidic, neutral, and basic compounds in blood and urine.
This application from UCT describes an easy, fast, and effective method using QuEChERS for the quantitative analysis of benzodiazepines in whole blood.
This application note from UCT details a suggested procedure for the simultaneous determination of prescription and designer benzodiazepines in urine by SPE and LC-MS/MS.
UCT has produced an application note outlining a suggested procedure for in-well hydrolysis of urine samples using the company's Refine™ Ultra-Filtration Technology. Using this technology reduces column backpressure while also reducing analyte...
UCT has produced an application note outlining a suggested procedure that reduces column backpressure while also reducing analyte suppression, when compared to a standard dilute and shoot protocol. Using UCT’s Refine™ Ultra-Filtration Technology...
Would a modified QuEChERS approach help you to analyse complex biological matrices? If so, this presentation will show you how to apply a QuEChERS method for sample clean-up of one of toxicology’s more difficult specimens to handle, post-mortem...
UCT has produced an application note for the determination of 78 banned or controlled racing industry drugs in horse urine using SPE and LC-MS/MS.
UCT has produced an application note presenting a rapid, three-step SPE procedure for the identification and quantification of fentanyl and its major urinary metabolite norfentanyl, in addition to four “designer” compounds: U-47700, W-18, W-15 and...
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