Bioclinical Analysis

LC-MS analysis of thyroid hormones in human serum

Thyroid hormones play critical roles in the regulation of biological processes, such as growth, metabolism, protein synthesis, and brain development. Specifically, both 3,3’,5,5’-tetraiodo-L-thyronine (thyroxine or T4) and 3,3’,5-triiodo-L...

Analysing mycotoxins in hemp-derived CBD oils by LC-MS/MS

Struggling with mycotoxin analysis in CBD oils? Need some method development help with your sample preparation and chromatography? Why not register for the 'Analytical Testing Strategies for Medical Use Cannabis' eSeminar to find out more...

A simple dilute-and-shoot method for the analysis of fentanyl and its analogues in human urine by LC-MS/MS

This application note from Restek presents a simple dilute-and-shoot method that provides a fast 3.5 minute analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and...

Simultaneously analyse catecholamines and metanephrines in urine by LC-MS/MS

Restek has produced an application note introducing a simple solid-phase extraction procedure for the simultaneous analysis of catecholamines and metanephrines in urine that is suitable for high-throughput clinical diagnostics.

Reducing analyte suppression and HPLC column backpressure

UCT has produced an application note outlining a suggested procedure that reduces column backpressure while also reducing analyte suppression, when compared to a standard dilute and shoot protocol. Using UCT’s Refine™ Ultra-Filtration Technology...

    

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