Bioclinical Analysis

A simple dilute-and-shoot method for the analysis of fentanyl and its analogues in human urine by LC-MS/MS

This application note from Restek presents a simple dilute-and-shoot method that provides a fast 3.5 minute analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and...

Simultaneously analyse catecholamines and metanephrines in urine by LC-MS/MS

Restek has produced an application note introducing a simple solid-phase extraction procedure for the simultaneous analysis of catecholamines and metanephrines in urine that is suitable for high-throughput clinical diagnostics.

Reducing analyte suppression and HPLC column backpressure

UCT has produced an application note outlining a suggested procedure that reduces column backpressure while also reducing analyte suppression, when compared to a standard dilute and shoot protocol. Using UCT’s Refine™ Ultra-Filtration Technology...

     

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