Bioclinical Analysis

Quantification of immunosuppressants in human blood by liquid chromatography-tandem mass spectrometry

This technical note describes the implementation of an analytical method for the quantification of four immunosuppressants (tacrolimus, sirolimus, everolimus, and cyclosporine A) in human blood on a Thermo Scientific™ TSQ Quantis™ triple quadrupole...

Perform quantitative analysis of benzodiazepines by QuEChERS and LC-MS/MS

This application from UCT describes an easy, fast, and effective method using QuEChERS for the quantitative analysis of benzodiazepines in whole blood.

Simultaneously determine prescription and designer benzodiazepines in urine by SPE and LC-MS/MS

This application note from UCT details a suggested procedure for the simultaneous determination of prescription and designer benzodiazepines in urine by SPE and LC-MS/MS.

A simple dilute-and-shoot method for the analysis of fentanyl and its analogues in human urine by LC-MS/MS

This application note from Restek presents a simple dilute-and-shoot method that provides a fast 3.5 minute analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and...

Determination of Racing Industry Drugs in Horse Urine Using SPE and LC-MS/MS

UCT has produced an application note for the determination of 78 banned or controlled racing industry drugs in horse urine using SPE and LC-MS/MS.

Analysis of Synthetic Opiates and Novel Analgesics in Urine using SPE and HPLC-MS/MS

UCT has produced an application note presenting a rapid, three-step SPE procedure for the identification and quantification of fentanyl and its major urinary metabolite norfentanyl, in addition to four “designer” compounds: U-47700, W-18, W-15 and...

High-Throughput Dynamic Light Scattering Instrument with 21CFR11 Compliance

Wyatt Technology, a leader in instrumentation for absolute macromolecular and nanoparticle characterization, announces the release of its 21CFR11-compliant software for its groundbreaking DynaPro® Plate Reader II (PRII). The DynaPro PRII is said to...

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