Bioclinical Analysis

In this presentation from a recent 'Advances in Forensics & Toxicology eSeminar' hosted by Separation Science in collaboration with Bruker, Bjorn Moosmann provides a convenient workflow for rapidly updating screening methods for the detection of...

In this application note from Agilent Technologies hydrophobic interaction chromatography (HIC) is used for the determination of the drug-to-antibody ratio (DAR) of a cysteine-linked antibody drug conjugate (ADC).

This application note from UCT details a suggested procedure for the simultaneous determination of prescription and designer benzodiazepines in urine by SPE and LC-MS/MS.

This poster from Biotage compares sample preparation options for the extraction of a panel of endogenous steroids from serum.

This application note from Restek presents a simple dilute-and-shoot method that provides a fast 3.5 minute analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and...

This application note from Agilent Technologies shows the development of an SFC method for the chiral separation of D- and L-amphetamine and the analysis of an authentic whole blood sample.

UCT has produced an application note outlining a suggested procedure for in-well hydrolysis of urine samples using the company's Refine™ Ultra-Filtration Technology. Using this technology reduces column backpressure while also reducing analyte...

Restek has produced an application note introducing a simple solid-phase extraction procedure for the simultaneous analysis of catecholamines and metanephrines in urine that is suitable for high-throughput clinical diagnostics.

UCT has produced an application note outlining a suggested procedure that reduces column backpressure while also reducing analyte suppression, when compared to a standard dilute and shoot protocol. Using UCT’s Refine™ Ultra-Filtration Technology...

This study demonstrates the use of flow-modulated GC×GC to analyse complex cannabis extracts, with simultaneous detection by TOF MS for confident identification and FID for robust quantitation.

Agilent Technologies has produced an application note describing the absolute quantification of snake venom proteins. Using capillary LC to separate the proteins, followed by sulfur determination using isotope dilution ICP-QQQ, accurate...

Biotage has produced an application note describing the extraction of a panel of steroid hormones from human serum using ISOLUTE^® SLE+ Supported Liquid Extraction plates prior to LC/MS-MS analysis.