Bioclinical Analysis

Extraction of Plasma Catecholamines and Metanephrines using SPE Prior to LC-MS/MS Analysis

Biotage has produced an application note describing a mixed-mode weak cation exchange SPE protocol for extraction of three catecholamines and three metanephrine metabolites from plasma prior to LC-MS/MS detection.

Robust Method for Analysis of Immunosuppressant Drugs in Blood

Thermo Fisher Scientific has produced an application note to demonstrate the robustness of the Thermo Scientific™ TSQ Quantis™ triple quadrupole mass spectrometer by analysis of immunosuppressant drugs in whole blood for clinical research.

A Perfect Tool for the Determination of Trace Elements in Blood and Serum

PerkinElmer has produced an application note demonstrating the advantages of the NexION 2000® ICP-MS for trace elemental analysis in blood and serum and explores the ability to simplify sample preparation, which is a direct result of the...

Quantification of Compounds in the E7 Liquid Crystal Mixture by SFC with UV Detection

Agilent Technologies has produced an application note demonstrating the capability of the Agilent 1260 Infinity Analytical SFC system to perform quantitative analysis of liquid crystal compounds.

Analysis of Tryptic Digests of a mAb and an ADC with the Agilent 1290 Infinity II LC

Agilent Technologies has produced an application note describing the analysis of tryptic digests of the monoclonal antibody (mAb) trastuzumab, or trade name Herceptin, and the antibody-drug conjugate (ADC) ado-trastuzumab emtansine, or trade name...

Extraction of Illicit Drugs and Pesticides from Liver Tissue Prior to GC-MS Analysis

Biotage has produced an application note describing the extraction of a broad range of analytes from liver tissue matrix prior to GC/MS analysis using ISOLUTE ® SLE+ supported liquid extraction columns. 
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