This technical article discusses the process of hot split injections and the sources of discrimination, which are one of the potential downsides of this technique.
Dr Matthew Klee
Dr Matthew S. Klee is internationally recognized for contributions to the theory and practice of gas chromatography. His experience in chemical, pharmaceutical, and instrument companies spans over 30 years. During this time, Dr Klee’s work has focused on elucidation and practical demonstration of the many processes involved with GC analysis, with the ultimate goal of improving the ease of use of GC systems, ruggedness of methods and overall quality of results.
Recent Posts
This article will discuss split injections with a hot split/splitless inlet. This is the most popular inlet and sampling mode for capillary GC. The focus will be on the basic concepts and flow paths. Later articles will cover liner choice,...
This technical article provides a general overview of the purpose of GC columns, key processes involved and a description of differences between them.
This technical article covers the general function of GC inlets and describes some common attributes and differences whilst providing a context for future articles covering inlets in more detail.
These articles will provide clear and simple explanations of the various equipment and processes involved with GC analysis so that everyday users are more comfortable and more effective at getting their jobs done and providing high-quality...
Posts by Topic
- Gas Chromatography (GC) (119)
- Learning & Training (46)
- GC-MS (36)
- Webinars & eSeminars (33)
- Methods & Applications (11)
- Two-dimensional Gas Chromatography (GCxGC) (10)
- GC Learning Hub (9)
- GC-TOFMS (8)
- tutorial (8)
- GC×GC-ToF-MS (7)
- Mass Spectrometry (MS) (7)
- Videos & Tutorials (7)
- hydrogen (6)
- Analytical Training Solutions (5)
- Columns (5)
- Environmental Water (5)
- GC-MS/MS (5)
- Method Development (5)
- Sample Preparation (5)
- Solid Phase Microextraction (SPME) (5)
- Environmental (4)
- Troubleshooting (4)
- Food Safety (3)
- Metabolomics (3)
- Cannabis Testing (2)
- Food Quality (2)
- Petrochemical (2)
- Solid Phase Extraction (SPE) (2)
- TOF-MS (2)
- Thermal desorption (2)
- Breath Analysis (1)
- Chromatography Software (1)
- Cosmetics (1)
- Environmental Atmospheric (1)
- Environmental Pesticide Analysis (1)
- Food Contaminants (1)
- Food Flavours & Fragrances (1)
- Food Ingredients (1)
- LC-MS (1)
- LC-MS/MS (1)
- Lab Operations (1)
- Lab Productivity (1)
- Liquid Chromatography (LC) (1)
- PAH (1)
- Petrochemicals (1)
- Pharma Clinical Diagnostics (1)
- Pharma Quality Assurance (1)
- QC (1)
- Smart GC (1)
- VOCs (1)
- biofuels (1)
- carrier gas (1)
- eBook (1)
- gas leaks (1)
- headspace (1)
- helium (1)
- high throughput (1)
