In this on-demand presentation, some examples of applications of different NMR structural techniques with cases from late lead optimization and preclinical development phase will be presented and discussed. Focus will be given also to the combined use of techniques to result in the full physical-chemical profile of the selected drug candidates.
Raman spectroscopy is an inelastic scattering technique that reveals vibrational spectra of molecules. When the excitation wavelength is tuned to fall within an absorption band of a chromophore, the Raman effect is called resonance Raman scattering.
[On-demand webinar] Vibrational spectroscopies constitute a diverse set of techniques that can provide valuable information about the structure and behaviour of any biological molecule under a wide range of experimental conditions. As such, the family of Raman and infrared spectroscopies are making significant impact in biology both for research and for applications in detection,...
Learn about accurate quantification of lipophilic toxins in shellfish and why it is important in food safety and often hampered due to lack or limited availability of authentic standards. To solve the problem, we investigated calibration of representative lipophilic shellfish toxin standards, DTX1, OA and YTX, by quantitative NMR (qNMR) using Certified Reference Material (CRM) as internal...
[On-demand webinar] Molecular recognition by specific targets is at the heart of the life processes. In recent years, it has been shown that the interactions between proteins (lectins, enzymes, antibodies) and carbohydrates mediate a broad range of biological activities, from fertilization, embryogenesis, and tissue maturation, to pathological processes.
This on-demand webinar lecture by Apostolos Spyros will provide an overview of the different applications of liquid and solid state NMR in food analysis. You will learn about the broad array of analytical problems that can be tackled with NMR spectroscopy, including food authenticity, quality control and adulteration.
Attend this on-demand webinar presented by Prof Jihad René Albani (Université des Sciences et Technologies de Lille, France) and through experimental examples you will discover the origin of fluorescence lifetimes of L-tryptophan free in solution and in peptides and proteins.
Attend this on-demand webinar by Carla Marchioro and you will learn how structural techniques contribute to drug discovery and development. This will be further explained through application examples.
[On-demand webinar] A novel method was developed to predict Long Residue properties as well as Short Residue properties at different flashing temperatures based on the IR spectrum of a crude oil measured at room temperature. The resulting demonstrates that this integrated approach offers a fast and viable alternative for the currently applied elaborative ASTM and IP methods (patented).
This on-demand talk will review applications of Raman spectroscopy in the pharmaceutical industry. The most common application of Raman spectroscopy is raw material identification. We will discuss the benefits, advantages as well as the limitations of Raman spectroscopy for raw material identification and finished product verification.