Separation Science

Perform Analysis of Choline and Acetylcholine in Rat Cerebrospinal Fluid Samples by SFC

Shimadzu has produced an application note describing the SFC analysis of choline in a rat cerebrospinal fluid sample by direct injection of the cerebrospinal fluid to the Nexera-UC system.

Effective Analysis and Evaluation of Chiral Drugs in Biological Samples using SFC-MS/MS

Shimadzu has produced an application note describing the application of SFC-MS/MS methods for bioanalysis of enantiomeric drugs, taking omeprazole and rabeprazole as examples.

Application of Online SFE-SFC-PDA for Cleaning Validation

Shimadzu has produced an application note describing the Nexera-UC online SFE-SFC system that was used for efficient analysis of alkylbenzenesulfone from a swab (cloth used for surface wiping to show safety at a pharmaceutical manufacturing site).

Perform Quantitative Analysis of Highly Polar Pesticides in Food Using SFC-MS

Shimadzu has produced an application note demonstrating an example of batch analysis of highly polar pesticides using SFC that may be effective for analyses for which retention and separation are difficult in LC.

Supercritical Fluid Chromatography with Flexible Injection Volumes at Highest Precision

Agilent Technologies has produced a Technical Overview demonstrating the injection principle used in the Agilent 1260 Infinity II SFC Multisampler. In this instrument, the sample volume is drawn under atmospheric pressure conditions, pressurized...


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