Separation Science

Achieve high-throughput analysis of cannabinoids by LC-UV

The LC-UV method shown in this application note from Restek uses a Raptor ARC-18 column to fully resolve 16 major and most frequently observed minor cannabinoids for which commercial standards are available.

Reduce your current GC-MS analysis time and get results faster

Would you like to significantly reduce your current GC-MS analysis time while maintaining the same chromatographic separation? The combination of using a GC Accelerator oven insert kit and adapting an existing method to a scaled-down, more...

Analysis of fragranced consumer products using TD–GC–MS

Markes International has produced an application note describing the analysis of three fragranced consumer products – fabric conditioner, washing detergent and washing powder – using three sampling approaches in conjunction with analysis by...

The effects of LC particle choice on column performance

In this technical note from Restek, the performance of Raptor™ 5 μm SPP LC columns to traditional 3 and 5 μm FPP LC columns is compared. Furthermore, it is demonstrated how faster, more efficient analyses can be attained with greater sensitivity...

Developing Strategies for Preparative HPLC

Agilent Technologies has produced a technical overview describing how to combine UV- and mass-based fraction detection with recovery collection for confident, successful sample purification.

HPLC Column Selection Guide to Help You Achieve the Best Separation

Dr Christian Hirsch from Shodex has compiled a comprehensive HPLC column selection guide to help you select the right HPLC column for your application and achieve the best separation out of your HPLC measurements.

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Shimadzu Launches i-Series Plus Integrated HPLC System

Shimadzu has launched its i-Series Plus integrated HPLC system that covers conventional to ultra-fast LC analysis. The launch coincides with the company's 50th anniversary of its presence in Europe.

GPC/SEC Analysis of Polymer Branching

Malvern has produced an application note describing the GPC (or equivalently SEC) analysis of branching in polyvinylpyrrolidone (PVP).

Characterizing Different Polymer Degradation Routes during Processing using Multi-detector GPC and Capillary Rheology

Malvern has produced an application note describing molecular and rheological changes that occurred as samples of PS and PMMA were extruded through a capillary rheometer, simulating moulding.

Perform Analysis of Choline and Acetylcholine in Rat Cerebrospinal Fluid Samples by SFC

Shimadzu has produced an application note describing the SFC analysis of choline in a rat cerebrospinal fluid sample by direct injection of the cerebrospinal fluid to the Nexera-UC system.

Effective Analysis and Evaluation of Chiral Drugs in Biological Samples using SFC-MS/MS

Shimadzu has produced an application note describing the application of SFC-MS/MS methods for bioanalysis of enantiomeric drugs, taking omeprazole and rabeprazole as examples.

Application of Online SFE-SFC-PDA for Cleaning Validation

Shimadzu has produced an application note describing the Nexera-UC online SFE-SFC system that was used for efficient analysis of alkylbenzenesulfone from a swab (cloth used for surface wiping to show safety at a pharmaceutical manufacturing site).

     

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