Separation Science

The effects of LC particle choice on column performance

In this technical note from Restek, the performance of Raptor™ 5 μm SPP LC columns to traditional 3 and 5 μm FPP LC columns is compared. Furthermore, it is demonstrated how faster, more efficient analyses can be attained with greater sensitivity...

Developing Strategies for Preparative HPLC

Agilent Technologies has produced a technical overview describing how to combine UV- and mass-based fraction detection with recovery collection for confident, successful sample purification.

HPLC Column Selection Guide to Help You Achieve the Best Separation

Dr Christian Hirsch from Shodex has compiled a comprehensive HPLC column selection guide to help you select the right HPLC column for your application and achieve the best separation out of your HPLC measurements.

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Shimadzu Launches i-Series Plus Integrated HPLC System

Shimadzu has launched its i-Series Plus integrated HPLC system that covers conventional to ultra-fast LC analysis. The launch coincides with the company's 50th anniversary of its presence in Europe.

GPC/SEC Analysis of Polymer Branching

Malvern has produced an application note describing the GPC (or equivalently SEC) analysis of branching in polyvinylpyrrolidone (PVP).

Characterizing Different Polymer Degradation Routes during Processing using Multi-detector GPC and Capillary Rheology

Malvern has produced an application note describing molecular and rheological changes that occurred as samples of PS and PMMA were extruded through a capillary rheometer, simulating moulding.

Perform Analysis of Choline and Acetylcholine in Rat Cerebrospinal Fluid Samples by SFC

Shimadzu has produced an application note describing the SFC analysis of choline in a rat cerebrospinal fluid sample by direct injection of the cerebrospinal fluid to the Nexera-UC system.

Application of Online SFE-SFC-PDA for Cleaning Validation

Shimadzu has produced an application note describing the Nexera-UC online SFE-SFC system that was used for efficient analysis of alkylbenzenesulfone from a swab (cloth used for surface wiping to show safety at a pharmaceutical manufacturing site).

High-Precision Temperature Control for SFC Using the Agilent 1260 Infinity II Multicolumn Thermostat

Agilent Technologies has produced a Technical Overview demonstrating the use of the Agilent 1260 Infinity II Multicolumn Thermostat in the Agilent InfinityLab Supercritical Fluid Chromatography (SFC) Solution. It describes how the post column...

How to Achieve High Temperature GPC Analysis of Polyphenylene Sulfide

Tosoh Bioscience has produced an application note describing how polyphenylene sulfide (PPS) analysis can be successfully achieved using its EcoSEC high temperature GPC system.

Effective Analysis of Asphalt Binders

Tosoh Bioscience has produced an application note describing the analysis of asphalt binders using gel permeation chromatography.

Analysis of Bio-Inspired Alkylalanoid Polymers

Tosoh Bioscience has produced an application describing how to improve reproducibility of MW measurements of polypeptoids using an EcoSEC GPC system.