Pharmaceutical Analysis Blog

PREP 2019 Symposium and Exhibit on Preparative and Process Chromatography

PREP 2019 takes place 7-10 July this year in Baltimore - find out more about what's going on and why you should think about attending... PREP 2019 is the longest running, most recognized international scientific conference and exposition in the world driving the field of Preparative and Process Chromatography.

PREP Symposium 2019

The program is packed with papers on biomolecules, including monoclonal antibodies, antibody fragments and other non-mAb therapeutic proteins, protein charge variants, virus, VLPs, plasmids, and stem cells, small molecules, including APIs, peptides, oligonucleotides, and natural products, chromatographic modalities including RP-HPLC, IEC, HIC, MMC, affinity, small-scale prep for drug discovery, development and manufacture, SMB and other multicolumn chromatography systems, continuous and integrated processing, new operating modalities, SFC, CPC, membrane chromatography, and monoliths.

In addition, you will find sessions dedicated to new, improved, and innovative stationary phases, sessions focused on understanding column packing, as well as sessions dedicated to advances in modeling and optimizing chromatographic processes.

The program comprises oral sessions of invited and contributed talks, presentations by exciting young scientists, vendor-sponsored technical workshops, practical educational workshops, tutorials, and an abundance of networking opportunities.

Meanwhile, the exposition will showcase the latest advances in chromatographic media, equipment, and services. Throughout the exhibition hall you will find high quality scientific posters competing for awards in the best poster competition, new and innovative products, major launches of new products, ground-breaking technologies, and experts in the booths who will be available to discuss challenges and offer solutions that you will be able to take back to your lab.

The oral program includes 72 papers of which 61% of the papers are from industry and 39% from academia. Countries represented in the oral program include Austria, France, Germany, Hungary, Japan, Mexico, Poland, Portugal, Singapore, Slovenia, Sweden, Switzerland, the UK, and the US.

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1. Keynote Session: Industrial Case Studies in Protein Chromatography
2. Innovative Stationary Phases and Processes
3A. Process Modeling – I
3B. Stationary Phases – I
4A. Process Modeling – II
4B. Stationary Phases – II
5. Keynote Session: Preparative Chromatography in Drug Discovery, Development, and Manufacture
6. Keynote Session: Continuous Chromatography
7A. QbD in Biopharmaceutical Process Development and Manufacturing
7B. Stationary Phases – III
8A. Alternative Chromatographic Processes
8B. Continuous Processes
9. Keynote Session: Peptides and Oligonucleotides
10. Fundamentals Applied to Understand Chromatography Columns
11. Monoliths and Membrane Chromatography
12. Applications to Virus, VLPs, Plasmids, and Cell Purification


Topics include, but are not limited to the following areas:

* Preparative and process chromatography
* Regulatory aspects and process validation
* HPLC, medium, and low pressure liquid chromatography
* High throughput screening (HTS) and HTPD
* Small-scale preparative chromatography
* Proteins, mAbs, ADCs, and other biopharmaceuticals
* Stationary phases (SEC, RPC, HIC, IEX, MMC, Protein A, Affinity, Hydroxyapatite)
* Fusion protein and conjugates
* Membrane chromatography and Monoliths
* Plasmids
* Column packing, packing stability, and large-scale columns
* Vaccines
* Single use equipment and flexible processes
* VLPs
* Laboratory equipment and process scale systems
* Cell separations for cell therapy and other applications
* Process modeling tools and software
* Fine chemicals and active pharmaceutical ingredients
* Simulated Moving Bed and multicolumn processes
* Chiral molecules
* Continuous and integrated processing
* Peptides and oligonucleotides
* Expanded bed adsorption
* Chromatography to support medicinal chemistry
* Supercritical Fluid Chromatography (SFC)
* Amino acids
* Sugars
* Fundamentals, Modeling and Optimization
* Rare earths
* Economics of chromatographic processes
* Natural products
* Quality by Design (QbD) and Design of Experiments (DoE)
* Environmental sustainability - process intensification, solvent and energy reduction
* Big data approaches in chromatography


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PREP & ISPPP...full day overlap for joint technical program activities
For people seeking comprehensive coverage of bio-chromatography from process scale to analytics, a single, discounted registration fee will provide access to both the PREP 2019 and the ISPPP 2019 Conference on the separation, purification and characterization of biologically important molecules that will be held the same week in the same conference venue. Both conferences will organize a full day overlap for joint technical program activities to take advantage of technical content and networking synergies. Registered participants from either conference may attend any PREP and ISPPP session that takes place on Wednesday, July 10, 2019. 



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