Peptide mapping is critical for characterizing protein drugs and monitoring product critical quality attributes (CQAs) in biopharma. Due to the heterogenous nature of protein drugs, comprehensive analytical characterization is required for getting full coverage peptide maps and identifying heterogeneities, such as post-translation modifications (PTMs). Sample preparation can be tedious, time consuming and error prone. Separation and detection require sensitivity to a broad molecular range to ensure that nothing is missed, and you need software, designed specifically for biopharma, to turn your data into answers. You need complete confidence in your results, all with growing pressure for speed and increased productivity.
Separation Science, in collaboration with Agilent Technologies, is offering an on-demand webinar presentation that discusses a fast and sensitive workflow for in-depth peptide mapping and PTM analysis. The talk is given by Linfeng Wu, an LC-MS application scientist at Agilent Technologies, who will be joined for the Q&A session by her colleague Ning Tang. Linfeng has extensive experience in biochemical analysis, mainly focusing on proteomics and biopharmaceutical analysis. Prior to her current role, Linfeng worked as a researcher concentrated on protein biomarker discovery and multi-omics integration in personalized medicine.
By viewing this presentation you will learn:
- How an integrated peptide mapping workflow solution automates and streamlines this complex process from sample preparation to data analysis.
- How a new LC/Q-TOF acquisition method–Iterative MS/MS– makes method optimization easy and improves the sensitivity and confidence for low abundant peptide.
- How this integrated workflow makes identification and quantification for PTM peptides fast and simple.
Don't miss out on how to improve your peptide mapping and PTM analysis skills and register to view this presentation, particularly if you are an application chemist, biopharma scientist or process chemist.