Microscopy Solutions Blog

Cancer Research: Extract Undiluted Cancer Tissue for DNA Mutation Analysis

Leica's laser microdissection systems are said to improve workflow by precisely cutting only the cells of interest. Every step is under visual control and proceeds without contamination with surrounding tissue.

 Discover how laser microdissection can improve your workflow >>

Leica_laser_microdissection.pngImprove your workflow with Laser Microdissection
DNA mutations lead to abnormal proteins or missing functional proteins, which can cause cells to multiply uncontrollably and become cancerous. To find and understand the underlying mutation for a specific cancer type, extraction of pure tumour material is extremely important. This is challenging especially if only a limited amount of cancerous tissue is available (small metastasis, for example).

Laser microdissection allows for the extraction of purely cancerous tissue without contaminating your sample with healthy cells. DNA sequencing will lead to valid and reproducible results helping to identify the cancer causing DNA mutation easily as no masking by contaminating healthy cells can occur.

 

 

Typical fields of research

  • Pathology research
  • Neuroscience
  • Pharmaceutical research
  • Plant research
  • Epigenetics research

Discover how laser microdissection can improve your workflow >>

 

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