Confirming the Presence of Cannabinoids in Cannabis sativa by HPTLC-MS

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In recent years a lot of research has been done on the medicinal use of Cannabis sativa. Cannabinol (CBN), cannabidiol (CBD) and Δ9-tetrahydrocannabinol (Δ9-THC) are the most studied active ingredients for medicinal use treating several health disorders such as migraine, epilepsy and appetite loss. In addition to its medicinal use cannabis has been legalized by several countries as marihuana.

This application note describes an HPTLC-MS method that offers a rapid way for substance confirmation, which can be used for screening and for quality control. Several samples can be separated in parallel and only the zones of interest are analysed, generating less data.

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