[Charged Aerosol Detection Bibliography]
See how other labs use this novel detection method
Since its introduction, charged aerosol detection has become the preferred universal LC detector for both routine and complex analyses. Charged aerosol detection has the ability to measure any non-volatile and semi-volatile analytes at sub-nanogram levels, and does not require ionization or a chromophore. This bibliography highlights the breadth and scope of different analytical methods found in the literature.
Download this bibliography for a detailed list of published articles.
[Application Note]
Improving the quantitation of unknown impurity analysis using dual gradient HPLC with charged aerosol detection
[Application Note]
HPLC-Charged Aerosol Detection impurity profiling of carbocisteine using mixed-mode chromatography
[Application Note]
A highly sensitive high-performance liquid chromatography charged aerosol detection method for the quantitative analysis of polysorbate 80 in protein solution
Polysorbates are non-ionic surfactants commonly used in biotherapeutic formulations to prevent surface adsorption and stabilize proteins against aggregation. However the quantitative analysis of polysorbate is challenging due to its complexity and lack of natural UV chromophores, and is, therefore, difficult to analyze by UV detection.
Learn about the determination of Tween 80 in protein solution with a highly sensitive charged aerosol detection (CAD) method.
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