Gas Chromatography

New approach to identify novel biomarkers in breath

This on-demand webinar introduces a powerful end-to-end solution for comprehensive profiling of breath volatiles, using the combination of thermal desorption, two-dimensional GC and mass spectrometry.

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Format: On-demand

Duration: Approximately 45 minutes

Event Overview

Breath testing has been proposed as an elegant, non-invasive method to provide rapid diagnosis of diseases – from cancer to COVID-19 – enabling the delivery of precision medicine. In this presentation, we introduce a powerful end-to-end solution for comprehensive profiling of breath volatiles, using the combination of thermal desorption, two-dimensional GC and mass spectrometry.

Our guest speaker, Dr Amalia Berna from the Children’s Hospital of Philadelphia, then discusses the application of this state-of-the-art technology to identify breath biomarkers associated with COVID-19 infection in children, allowing it to be quickly differentiated from other respiratory illnesses.

By watching this presentation you will:

  • Find out how thermal desorption (TD) provides sample security and integrity in breath biomarker workflows
  • See how two-dimensional gas chromatography (GC×GC) allows you to discover more from breath samples
  • Learn about the advantages of BenchTOF2 mass spectrometers for sensitive detection, confident identification and easy-to-use workflows
  • See how smart software tools can automatically ‘spot the difference’ between breath profiles
  • Hear about the real-world application of this technology for the detection of biomarkers associated with COVID-19.

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The Presenters

Presenters:
MattEdwardsWebMatthew Edwards (Business Development Manager, Americas - SepSolve Analytical)
Matt studied analytical chemistry at the University of Waterloo, Ontario, Canada, with particular emphasis on multi-dimensional separations. Matt remains based in Waterloo, from where he oversees the development of new markets and opportunities in the Americas, as well as providing technical and sales support.

AmaliaBernaWebDr Amalia Berna (Senior Research Scientist - Children’s Hospital of Philadelphia)
Amalia received her PhD from the Catholic University of Leuven, Belgium where she studied the volatile organic profile of different fruits and its role on sensory attributes. Amalia Berna is currently a Senior Research Scientist in the Department of Pediatric at the Children’s Hospital of Philadelphia where she performs research in breath analysis and the discovery of potential biomarkers of pediatric infectious and non-infectious diseases.

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