Biopharmaceutical Analysis Blog

The role of light scattering in biopharmaceutical formulation development

Are you involved in biopharmaceutical research? Would you like to find out more about the role of light scattering and associated techniques in characterizing biological molecules? This presentation from Separation Science, in collaboration with Wyatt Technology, will provide the answers that you need for protein formulation development and characterization.

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Summary

Protein formulation development and characterization relies heavily on a set of analytical tools and techniques to accurately assess a molecule’s stability. This toolbox includes a standard set of tools that has come to us through industry wisdom and experience. 

Light scattering is increasingly considered a “standard” tool in the set, and it is a core part of Fujifilm’s approach to protein formulation development. The presenter will introduce how various types of light scattering measurements are used in his work and offer several case studies where light scattering data impacted the project direction or was the only way to accurately measure the product.

By viewing this presentation you will learn...

  • Fujifilm’s formulation development philosophy
  • The role of light scattering and associated techniques in characterizing biological molecules
  • Interesting case studies encountered at Fujifilm.

The Presenter

markspearsMark Spears is a Senior Scientist at Fujifilm Diosynth Biotechnologies in Research Triangle Park, NC. He earned a PhD from Georgia Tech in 2014 where his work focused on biocompatible polymer microstructures and resulted in several first-author publications. Mark previously worked at Wyatt Technology as an Applications Scientist; he developed expertise in light scattering techniques and biophysical characterization of polymers and proteins; he also supported business development and sales activity in the southeastern United States. In 2018, Mark joined the Formulation Development group at Fujifilm where he works primarily on protein formulations including analytical characterization and innovation. When not working, Mark loves spending time with his wife and son.

Discover the importance of light scattering in biopharmaceutical formulation  development >>

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