Biopharmaceutical Analysis Blog

Tosoh Bioscience has produced Volume 1 of its 'Bioprocessing Application Notebook' that comprises over twenty application notes covering important aspects of biopharmaceutical purification.

Are you looking for solutions to your biopharmaceutical workflows? Struggling with your intact protein analysis, or need help with glycosylation studies? If so Separation Science, in collaboration with Thermo Fisher Scientific, has developed an...

This application from Agilent describes the 2D-LC analysis of complex peptones. Active solvent modulation proved to be valuable to maintain chromatographic performance and avoid breakthrough in the second dimension.

Recently, the evolution of middle to large biomacromolecules such as peptides or proteins is apparent in the market of pharmaceutical drugs in addition to traditional active ingredients based on small molecules. The use of peptides for clinical...

Phosphorylated compounds such as nucleotides are known to interact with stainless steel components leading to recovery issues in HPLC and LC/MS. Instrument and column inertness ensure successful analysis. Discover more about the bio-inert...

The therapeutic potential of biologic modalities has increased, driving an inevitable move toward exploring more complex biotherapeutic molecule classes. As biotherapeutics become more complex, there is still a demand for superior quantification...

Looking for an effective method for monoclonal antibody analysis? SEC-MS could be the answer...

Are you involved in biopharmaceutical research? Would you like to find out more about the role of light scattering and associated techniques in characterizing biological molecules? This presentation from Separation Science, in collaboration with...

Biopharmaceuticals represent protein molecules produced by genetically engineered living cells using large scale industrial bioprocessing. The complexity of these molecules requires advanced analytical characterisation strategies to ensure that...

This study describes the LCMS bioanalysis of antibody drugs using the Fab-selective proteolysis "nSMOL Method" offering an improvement of reaction conditions for automated analyses.

Do you work with therapeutic recombinant mAbs? Need to understand the extent of post-translational modifications? If so, you'll be interested in this comparison of in-solution protein digestion approaches...

Are you looking for a comprehensive source of applications information for biopharmaceutical methods? If so, this biopharma applications compendium is what you need. Sign up to the Separation Science 'Biopharmaceutical Characterization Resource...